Results 31 to 40 of about 26,894 (233)

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

open access: yes, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Anders, Hans-Joachim   +3 more
core   +1 more source

Chemokine Receptors and Phagocyte Biology in Zebrafish. [PDF]

open access: yes, 2020
Phagocytes are highly motile immune cells that ingest and clear microbial invaders, harmful substances, and dying cells. Their function is critically dependent on the expression of chemokine receptors, a class of G-protein-coupled receptors (GPCRs ...
Sommer, F.   +6 more
core   +1 more source

Genetic Polymorphisms of CXCL8 (−251) Are Associated with the Susceptibility of Helicobacter pylori Infection Increased the Risk of Inflammation and Gastric Cancer in Thai Gastroduodenal Patients

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2019
CXC Chemokine Ligand 8 (CXCL8) plays an important role in gastric inflammation and in the progression of gastric cancer induced by Helicobacter pylori (H. pylori) infection.
Wongwarut Boonyanugomol   +5 more
doaj   +1 more source

CXC Chemokines in Cancer Angiogenesis and Metastases [PDF]

open access: yes, 2010
The tumor microenvironment is extremely complex that depends on tumor cell interaction with the responding host cells. Angiogenesis, or new blood vessel growth from preexisting vasculature, is a preeminent feature of successful tumor growth of all solid tumors.
Ellen C, Keeley   +2 more
openaire   +2 more sources

The role of CXC chemokines in pulmonary fibrosis [PDF]

open access: yesJournal of Clinical Investigation, 2007
The CXC chemokine family is a pleiotropic family of cytokines that are involved in promoting the trafficking of various leukocytes, in regulating angiogenesis and vascular remodeling, and in promoting the mobilization and trafficking of mesenchymal progenitor cells such as fibrocytes.
Robert M, Strieter   +2 more
openaire   +2 more sources

A commensal Helicobacter sp. of the rodent intestinal flora activates TLR2 and NOD1 responses in epithelial cells. [PDF]

open access: yesPLoS ONE, 2009
Helicobacter spp. represent a proportionately small but significant component of the normal intestinal microflora of animal hosts. Several of these intestinal Helicobacter spp.
Nadia Chaouche-Drider   +9 more
doaj   +1 more source

Sequence characterization and expression pattern analysis of chemokines CXCL13 and CXCL14 in Asian swamp eel

open access: yesAquaculture Reports, 2020
In the present study, we analyzed and identified two CXC chemokine ligands in the swamp eel, Monopterus albus. The open reading frames of MaCXCL13 and MaCXCL14 were 375 bp and 300 bp, which encoded putative proteins of 124 aa and 99 aa, respectively ...
Dingda Xu   +3 more
doaj   +1 more source

Pathophysiological impact of CXC and CX3CL1 chemokines in preeclampsia and gestational diabetes mellitus

open access: yesFrontiers in Cell and Developmental Biology, 2023
Diabetes-related pathophysiological alterations and various female reproductive difficulties were common in pregnant women with gestational diabetes mellitus (GDM), who had 21.1 million live births.
Amin Ullah   +4 more
doaj   +1 more source

Identification of Therapeutic Targets and Prognostic Biomarkers Among CXC Chemokines in the Renal Cell Carcinoma Microenvironment

open access: yesFrontiers in Oncology, 2020
Background: Renal cell carcinoma (RCC) is one of the most common malignances with an ever-increasing incidence and high mortality. Cross-talk between cancer cells and interstitial cells exerts significant effects on neoplasia and tumor development and is
Qingquan Zeng   +5 more
doaj   +1 more source

Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis

open access: yesBMC Cancer, 2004
Background The Duffy antigen receptor for chemokines (DARC) is known to be a promiscuous chemokine receptor that binds a variety of CXC and CC chemokines in the absence of any detectable signal transduction events.
Burdick Marie D   +3 more
doaj   +1 more source

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