Results 41 to 50 of about 34,737 (208)

Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity

Frontiers in Microbiology, 2019
Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif, Norihito Ueda, Yoshio Nakatani, Lyn M. Wise, Sheree Clifton, Zabeen Lateef, Andrew A. Mercer, Stephen B. Fleming   +7 more
doaj   +1 more source

Cytokines of Birds: Conserved Functions [PDF]

, 2001
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F., Kaspers, Bernd, Puehler, Florian, Schneider, Kirsten, Staeheli, Peter   +4 more
core   +1 more source

Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection. [PDF]

PLoS Pathogens, 2010
Chemokines have been found to exert direct, defensin-like antimicrobial activity in vitro, suggesting that, in addition to orchestrating cellular accumulation and activation, chemokines may contribute directly to the innate host response against ...
Matthew A Crawford, Marie D Burdick, Ian J Glomski, Anne E Boyer, John R Barr, Borna Mehrad, Robert M Strieter, Molly A Hughes   +7 more
doaj   +1 more source

Chemotactic Cues for NOTCH1-Dependent Leukemia [PDF]

, 2018
The NOTCH signaling pathway is a conserved signaling cascade that regulates many aspects of development and homeostasis in multiple organ systems.
Amadori, Alberto, Piovan, Erich, Tosello, Valeria, Zanovello, Paola   +3 more
core   +1 more source

Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis

BMC Cancer, 2004
Background The Duffy antigen receptor for chemokines (DARC) is known to be a promiscuous chemokine receptor that binds a variety of CXC and CC chemokines in the absence of any detectable signal transduction events.
Burdick Marie D, Belperio John A, Addison Christina L, Strieter Robert M   +3 more
doaj   +1 more source

Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]

, 2001
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers, E.J. Pishko, HARMON B.G., K.C. Weining, KLEIN J.B., KOGUT M.H., KOGUT M.H., LEINO L., M.H. Kogut, MERRILL G.A., SETO F., STICKLE J.F., WEINING K.C.   +12 more
core   +1 more source

β2-adrenergic agonists modulate TNF-α induced astrocytic inflammatory gene expression and brain inflammatory cell populations [PDF]

, 2014
Background: The NF-kappa B signaling pathway orchestrates many of the intricate aspects of neuroinflammation. Astrocytic beta(2)-adrenergic receptors have emerged as potential regulators in central nervous system inflammation and are potential targets ...
Aerts, Joeri L, De Keyser, Jacques, Demol, Frauke, Gerlo, Sarah, Laureys, Guy, Spooren, Anneleen   +5 more
core   +3 more sources

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT, Bednar MM, Bellosta S, Buttrum SM, Buyon JP, Calara F, Calderon TM, Diacovo TG, Giroux LM, Jukema JW, Kim JA, Kimura M, Laufs U, Laws KH, Lehr H-A, Marcus AJ, Notabartolo A, Olstrowsky L, Pons F, Ruf A, Smalley DM, Stragliotto E, Sugiyama S, Weber C, Weber C, Weber C, Yeagle PL, Yeo EL, Yue TL   +28 more
core   +1 more source

Interleukin-6-Production Is Responsible for Induction of Hepatic Synthesis of Several Chemokines as Acute-Phase Mediators in Two Animal Models: Possible Significance for Interpretation of Laboratory Changes in Severely Ill Patients

Biology, 2022
A mild to moderate increase in acute-phase proteins (APPs) and a decrease in serum albumin levels are detected in hospitalized COVID-19 patients. A similar trend is also observed for acute-phase cytokines (APC), mainly IL6, besides chemokines (e.g ...
Ihtzaz Ahmed Malik, Giuliano Ramadori
doaj   +1 more source

Organ-specific features of natural killer cells. [PDF]

, 2011
Natural killer (NK) cells can be swiftly mobilized by danger signals and are among the earliest arrivals at target organs of disease. However, the role of NK cells in mounting inflammatory responses is often complex and sometimes paradoxical.
La Cava, Antonio, Ljunggren, Hans-Gustaf, Shi, Fu-Dong, Van Kaer, Luc   +3 more
core   +1 more source