Results 51 to 60 of about 19,999 (211)
CXC Chemokines in Cancer Angiogenesis and Metastases [PDF]
, 2010 The tumor microenvironment is extremely complex that depends on tumor cell interaction with the responding host cells. Angiogenesis, or new blood vessel growth from preexisting vasculature, is a preeminent feature of successful tumor growth of all solid tumors.
Ellen C, Keeley +2 more
openaire +2 more sources
The role of CXC chemokines in pulmonary fibrosis [PDF]
Journal of Clinical Investigation, 2007 The CXC chemokine family is a pleiotropic family of cytokines that are involved in promoting the trafficking of various leukocytes, in regulating angiogenesis and vascular remodeling, and in promoting the mobilization and trafficking of mesenchymal progenitor cells such as fibrocytes.
Robert M, Strieter +2 more
openaire +2 more sources
The role of CXCL family members in different diseases
Cell Death Discovery, 2023 Chemokines are a large family mediating a lot of biological behaviors including chemotaxis, tumor growth, angiogenesis and so on. As one member of this family, CXC subfamily possesses the same ability.
Chenjia Zhou +4 more
doaj +1 more source
Frontiers in Oncology, 2021 The CXC chemokines belong to a family which includes 17 different CXC members. Accumulating evidence suggests that CXC chemokines regulate tumor cell proliferation, invasion, and metastasis in various types of cancers by influencing the tumor ...
Yongchao Li +9 more
doaj +1 more source
Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody
mAbs, 2020 CXCR1 and CXCR2 signaling play a critical role in neutrophil migration, angiogenesis, and tumorigenesis and are therefore an attractive signaling axis to target in a variety of indications.
Jeffrey S. Boyles +10 more
doaj +1 more source
Frontiers in Microbiology, 2019 Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif +7 more
doaj +1 more source
Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection. [PDF]
PLoS Pathogens, 2010 Chemokines have been found to exert direct, defensin-like antimicrobial activity in vitro, suggesting that, in addition to orchestrating cellular accumulation and activation, chemokines may contribute directly to the innate host response against ...
Matthew A Crawford +7 more
doaj +1 more source
Re: Chemokines in Cancer [PDF]
, 2016 Chemokines are chemotactic cytokines that regulate the trafficking and positioning of cells by activating the seven-transmembrane spanning G protein-coupled chemokine receptors (GPCR) or non G protein-coupled seven-transmembrane spanning receptors called
Fehmi Narter
core +1 more source
Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer. [PDF]
Oncotarget, 2017 Tumor-infiltrating T-cells are strongly associated with prognosis in colorectal cancer, but the mechanisms governing intratumoral lymphocyte recruitment are unclear.
Kistner L +4 more
europepmc +2 more sources
Novel CXCR2â dependent liver regenerative qualities of ELRâ containing CXC chemokines [PDF]
, 1999 Severe acute liver injury due to accidental or intentional acetaminophen overdose presents a major clinical dilemma often requiring liver transplantation.
Lukacs, Nicholas W. +15 more
core +1 more source