Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]
, 2004 Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Anders, Hans-Joachim +3 more
core +1 more source
The role of CXC chemokines in the transition of chronic inflammation to esophageal and gastric cancer [PDF]
, 2012 <p>Chronic inflammation may increase the risk to develop cancer, for instance esophagitis or gastritis may lead to development of esophageal or gastric cancer, respectively.
S. Struyf +7 more
core +1 more source
Image_3_Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma.tif [PDF]
, 2021 BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Jiacheng Huang (1639390) +5 more
core +1 more source
BMC Immunology, 2008 Background The ELR+CXC chemokines are multifunctional mediators that are mainly responsible for the recruitment of leucocytes to sites of inflammation and infection.
Kezhi Xing +4 more
doaj +1 more source
Targeting Rac1 signaling inhibits streptococcal M1 protein-induced CXC chemokine formation, neutrophil infiltration and lung injury. [PDF]
PLoS ONE, 2013 Infections with Streptococcus pyogenes exhibit a wide spectrum of infections ranging from mild pharyngitis to severe Streptococcal toxic shock syndrome (STSS). The M1 serotype of Streptococcus pyogenes is most commonly associated with STSS.
Songen Zhang +5 more
doaj +1 more source
Understanding the immunoangiostatic CXC chemokine network [PDF]
Cardiovascular Research, 2008 Chemokines, originally discovered as mediators of directional migration of immune cells to sites of inflammation and injury, have a function beyond their role in leukocyte chemotaxis. Indeed, they participate in organ development, angiogenesis, tumourigenesis and, more importantly, in the immune response.
BALESTRIERI, Maria Luisa +3 more
openaire +4 more sources
Table_1_Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma.docx [PDF]
, 2021 BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Jiacheng Huang (1639390) +5 more
core +1 more source
Image_6_Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma.tif [PDF]
, 2021 BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Jiacheng Huang (1639390) +5 more
core +1 more source
The Novel Purification and Biophysical Characterization of CXC Chemokines [PDF]
, 2022 The chemokines are small, signaling proteins responsible for leukocyte recruitment through concentration gradient driven responses for inflammatory diseases such as tissue damage or sun burn, tumor suppression and regulation, and obesity from insulin ...
Martin, Patrick
core +1 more source
Image_7_Prognostic Biomarkers and Immunotherapeutic Targets Among CXC Chemokines in Pancreatic Adenocarcinoma.tif [PDF]
, 2021 BackgroundPancreatic cancer is one of the principal causes of tumor-related death worldwide. CXC chemokines, a subfamily of functional chemotactic peptides, affect the initiation of tumor cells and clinical outcomes in several human malignant tumors ...
Jiacheng Huang (1639390) +5 more
core +1 more source