Results 211 to 220 of about 54,272 (286)

Artificial Intelligence Integration With Nanotechnology for Cancer Therapy

MedComm, Volume 7, Issue 9, September 2026.
AI‐enabled nanotechnology provides a continuous learning framework for cancer therapy by integrating nanomaterial design, biological interactions, tumor delivery, clinical data, and therapeutic feedback to support predictive design, patient‐aware optimization, and improved translational decision‐making.
Shengbin Liu, Zhi Liu, Haixing Shi, Chengyi Wei, Ruijie Zhang, Xiangrong Song   +5 more
wiley   +1 more source

Multi-omics reveals a novel Cxcr4⁺ subpopulation of alveolar macrophages and therapeutic effect of AMD3100 in mice with advanced silicosis. [PDF]

Clin Transl Med
Mu M, Li B, Cao H, Zou Y, Yan R, Wang F, Zhao Y, Xie Z, Du M, Wu X, Tao X, Wang J.   +11 more
europepmc   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

MedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang, Jiangbo Fan, Wenyi Liu, Di Liu, Rui Wang, Yuanyang Wang, Jianhui Sun, Huacai Zhang, Qingli Cai, Zhe Xu, Fang Xu, Jianxin Jiang, Zhen Wang, Ling Zeng   +13 more
wiley   +1 more source

Tumor-associated macrophages and lineage plasticity in prostate cancer: from established myeloid programs to emerging spatial hypotheses. [PDF]

Front Immunol
Li J, Li J, Zhao Y, Yu Y, Cui X.
europepmc   +1 more source

Cancer Neuroscience: From Local Neuro–Immune Microenvironments to Systemic Brain–Body Circuitry

MedComm, Volume 7, Issue 9, September 2026.
This review outlines the cancer neuroscience paradigm, spanning systemic brain–body circuitry and local neuro–immune–tumor microenvironments. We discuss how tumors promote axonogenesis and pseudo‐synapse formation, and how sensory neuropeptides, such as CGRP, contribute to CD8+ T‐cell exhaustion.
Mingxuan Xie, Yu Zhao, Xinruo Xing, Yuqiang Liu, Jungang Zhao, Maojin Yao, Jun Tang, Jianzhu Zhao   +7 more
wiley   +1 more source

The CXCL12-CXCR4 axis in colorectal cancer: immune regulation, metastatic progression, and therapeutic implications. [PDF]

Front Immunol
Tian S, Liu J, Yang X, Guo J.
europepmc   +1 more source

Integrated Single‐Cell RNA Sequencing and Untargeted Metabolomics Reveals β‐Elemene's Immune and Metabolic Modulation in Triple‐Negative Breast Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
In a 4T1 TNBC model, β‐elemene suppressed tumor growth and pulmonary metastasis. scRNA‐seq showed it remodeled the tumor microenvironment by reducing cancer‐associated fibroblasts, enhancing antigen presentation, and inhibiting pro‐tumorigenic ECM remodeling. Metabolomics revealed prostaglandin downregulation.
Zhiqiang Luo, Guohua Yu, Huixia Fan, Ruofan Guo, Jingqi Zheng, Chen Wang, Ruyi Jin, Junhui Zhou, Jian Yang   +8 more
wiley   +1 more source

Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12. [PDF]

Aging Cell
Mahoney SA, Mazan-Mamczarz K, Tsitsipatis D, VanDongen NS, Henry-Smith C, Okereke AN, Munk R, Darvish S, Murray KO, De S, Gorospe M, Seals DR, Rossman MJ, Herman AB, Clayton ZS.   +14 more
europepmc   +1 more source

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao, Honghua Zhang, Jingyu Chen, Ziyu Qian, Ning Zhang, Yihua Zhang, Hui Ye, Jianbing Wu, Zhangjian Huang   +8 more
wiley   +1 more source

Attract to kill: Exploring the potential of motility trapping as a novel treatment strategy for high-grade gliomas. [PDF]

Neuro Oncol
Bamelis AS, Metselaar DS, Sie M, Lootens T, Willems L, Raedt R, Vandersteene J.   +6 more
europepmc   +1 more source