Results 241 to 250 of about 76,809 (334)

Mind the gap: renal tubule responses to injury and the role of Cxcl12 and Myc

, 2019
Veronika Sander, Richard W. Naylor, Alan J. Davidson   +2 more
openalex   +1 more source

The role of cytokines in ovarian cancer drug resistance

International Journal of Cancer, Volume 158, Issue 4, Page 821-834, 15 February 2026.
Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang, Yunxia Zang, Rebeka Dejenie, Junyuan Bing, Shixia Dong, Yanfei Zhang, Yi Zhu, Jingjing Li   +7 more
wiley   +1 more source

CXCR4-engineered fibroblast membrane nanovesicles for Photothermal-enhanced ferroptotic therapy through chemokine-navigated tumor homing. [PDF]

J Nanobiotechnology
Bai L, Tan YN, Zhang LF, Luo M, Luo J, Yang YM, Liu YZ, Ho-Fun Lee V, Feng-Ming Kong S, Guan XY.   +9 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, Volume 16, Issue 2, Page 432-446, February 2026.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

PRL-3 up-regulates exosomal ITGαvβ5 expression to promote liver pre-metastatic niche formation and colon cancer liver metastasis. [PDF]

Exp Hematol Oncol
Lan Q, Xu H, Zeng Y, Liu L, Hu X, Yang Q, Zhang Y, Liu W, Wu J, Weng J, He J, Xu X, Lai W, Chu Z.   +13 more
europepmc   +1 more source

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

, 2016
Claudia Sorrentino, Lucio Miele, Amalia Porta, Aldo Pinto, Silvana Morello   +4 more
openalex   +2 more sources

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, Volume 13, Issue 7, 3 February 2026.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

A gene-expression module identifies circulating immune cells with enhanced recruitment to sites of inflammation. [PDF]

iScience
Sinha D, Laurent T, Broquet A, Fourgeux C, Letellier T, Tilly G, Bruneau S, Ville S, Bouchet-Delbos L, Brancherau J, Kerleau C, Brouard S, Blancho G, Giral M, Josien R, Danger R, Roquilly A, Degauque N, Poschmann J.   +18 more
europepmc   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Age-dependent effects of chronic traumatic and social isolation stress on mice social behavior. [PDF]

Neurobiol Stress
Choi M, Jeong J, Kim D, Choi HS, Ryu J, Choi HJ, Cheon M, Jeong YH.   +7 more
europepmc   +1 more source