Results 11 to 20 of about 34,241 (258)

A clinical biomarker assay to quantitate CXCL9 in human serum

BioTechniques
To assess circulating CXCL9 as an exploratory biomarker in clinical studies, an electrochemiluminescence CXCL9 assay was validated in human serum to define assay conditions that can remove matrix effect, improve precision and accuracy, as well as ...
Lucia Franco-Dilone, Oitak Allen Wong, Omar F. Laterza, Xuemei Zhao   +3 more
doaj   +4 more sources

CXCL9 inhibition does not ameliorate disease in murine models of both primary and secondary hemophagocytic lymphohistiocytosis

Scientific Reports, 2023
Hemophagocytic Lymphohistiocytosis (HLH) is a group of disorders culminating in systemic inflammation and multi-organ failure with high incidence of hepatic dysfunction.
Tamir Diamond, Michelle Lau, Jeremy Morrissette, Niansheng Chu, Edward M. Behrens   +4 more
doaj   +2 more sources

The Role of CXCL13 and CXCL9 in Early Breast Cancer

Clinical Breast Cancer, 2020
Chemokines, cytokines in the immune microenvironment of tumors, may be associated with patient outcome. We assessed the impact of CXCL13 and CXCL9 on disease-free (DFS) and overall survival (OS), in an attempt to retrospectively evaluate both T and B cell function in the microenvironment of primary tumors from patients with breast cancer.Formalin-fixed
Razis, E., Kalogeras, K.T., Kotsantis, I., Koliou, G.-A., Manousou, K., Wirtz, R., Veltrup, E., Patsea, H., Poulakaki, N., Dionysopoulos, D., Pervana, S., Gogas, H., Koutras, A., Pentheroudakis, G., Christodoulou, C., Linardou, H., Pavlakis, K., Koletsa, T., Pectasides, D., Zagouri, F., Fountzilas, G.   +20 more
openaire   +4 more sources

CXCL9 expression in breast cancer and its correlation with the characteristics of tumor immunoinfiltration [PDF]

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Objective·To explore the effect of C-X-C motif chemokine ligand 9 (CXCL9) expression on the prognosis of breast cancer patients and its correlation with tumor-infiltrating immune cells (TIICs).Methods·Transcriptome data of 1 100 breast tumor tissues and ...
DU Shaoqian, TAO Mengyu, CAO Yuan, WANG Hongxia, HU Xiaoqu, FAN Guangjian, ZANG Lijuan   +6 more
doaj   +2 more sources

Serum CXCL9 levels are associated with tumor progression and treatment outcome in patients with nasopharyngeal carcinoma. [PDF]

PLoS ONE, 2013
OBJECTIVES: The aim of this cohort study was to examine the role of the chemokine (C-X-C motif) ligand 9 (CXCL9) on nasopharyngeal carcinoma (NPC). MATERIALS & METHODS: Sera from 205 NPC patients and 231 healthy individuals, and 86 NPC tumor samples were
Li-Jen Hsin, Huang-Kai Kao, I-How Chen, Ngan-Ming Tsang, Cheng-Lung Hsu, Shiau-Chin Liu, Yu-Sun Chang, Kai-Ping Chang   +7 more
doaj   +2 more sources

Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice [PDF]

Hepatology, 2012
Abstract Recent data suggest that the chemokine receptor CXCR3 is functionally involved in fibroproliferative disorders, including liver fibrosis. Neoangiogenesis is an important pathophysiological feature of liver scarring, but a functional role of angiostatic CXCR3 ...
MORENO ZALDIVAR, Mirko, Sahin, Hacer, Borkham-Kamphorst, Erawan, Kuppe, Christoph, Grouls, Christoph, Al-samman, Muhammad, Nellen, Andreas, Schmitz, Petra, Heinrichs, Daniel, Berres, Marie-Luise, Doleschel, Dennis, Scholten, David, Weiskirchen, Ralf, Moeller, Marcus J., Kiessling, Fabian, Trautwein, Christian, Wasmuth,   +16 more
openaire   +5 more sources

Plasma Levels of CXCL9 and MCP-3 are Increased in Asthma-COPD Overlap (ACO) Patients

International Journal of COPD
Jose Miguel Escamilla-Gil,1– 3 Carlos A Torres-Duque,2,3 Kevin Llinás-Caballero,1 Nadia Juliana Proaños-Jurado,2,3 María M De Vivero,1 Jonathan Camilo Ramirez,1 Ronald Regino,1 Lucila Teresa Florez de Arco,4 Rodolfo Dennis,5,6 Mauricio González-García,2 ...
Escamilla-Gil JM, Torres-Duque CA, Llinás-Caballero K, Proaños-Jurado NJ, De Vivero MM, Ramirez JC, Regino R, Florez de Arco LT, Dennis R, González-García M, Caraballo L, Acevedo N   +11 more
doaj   +2 more sources

ESAT6-Induced IFNγ and CXCL9 Can Differentiate Severity of Tuberculosis

PLoS ONE, 2009
Protective responses against Mycobacterium tuberculosis are dependent on appropriate T cell and macrophage activation. Mycobacterial antigen six kDa early secreted antigenic target (ESAT6) and culture filtrate protein 10 (CFP10) can detect M. tuberculosis specific IFNgamma responses.
Hasan, Zahra, Jamil, Bushra, Ashraf, Mussarat, Islam, Muniba, Yusuf, Muhammad S, Khan, Javaid A, Hussain, Rabia   +6 more
openaire   +6 more sources

The bioinfomatics analysis of the M1 macrophage-related gene CXCL9 signature in cervical cancer

Journal of Obstetrics and Gynaecology
Background The expression and function of coexpression genes of M1 macrophage in cervical cancer have not been identified. And the CXCL9-expressing tumour-associated macrophage has been poorly reported in cervical cancer.Methods To clarify the regulatory
Wenxin Liao, Tingting Liu, Yang Li, Hua Liang, Juexiao Deng, Fujin Shen   +5 more
doaj   +2 more sources

The influence of CXCL9 on M2 macrophages in lung cancer development. [PDF]

Transl Cancer Res
Lung cancer has the highest incidence among malignant tumors, and its high degree of metastasis and invasion, tendency to metastasis, and mortality rate are the key factors leading to treatment failure and poor prognosis. Tumor-associated macrophages (TAMs), which often exhibit an M2-polarized phenotype, are known to promote tumor progression. Notably,
Mi L, Xu L, Chen Z, Zheng Y.
europepmc   +3 more sources