Results 21 to 30 of about 34,241 (258)
Pathophysiological role of chemokine MIG/CXCL9 in the development of atopic dermatitis
Acta Biomedica Scientifica, 2022 Background. In patients with atopic dermatitis, the persistence of microorganisms on the skin surface is high, which can enhance the expression of MIG/CXCL9, exacerbating inflammation and activating keratinocyte apoptosis, however, the dynamics of this ...
I. V. Kibalina +3 more
doaj +3 more sources
Urinary CXCL9 and CXCL10 Levels and Acute Renal Graft Rejection.
International journal of organ transplantation medicine, 2019 Monitoring of chemokines, CXCL9 and CXCL10, in serum may present a non-invasive detection method for rejection.To investigate the relationship between urinary levels of CXCL9 and CXCL10 and graft function following renal transplantation.75 living-related donor renal transplant recipients were studied.
H Senturk Ciftci +14 more
openaire +3 more sources
Indian Journal of Dermatology, 2023 Background: Vitiligo is an acquired chronic autoimmune skin disorder with an estimated prevalence of 1% worldwide. The CD8+ T-cell-mediated chemokines such as CXCR3, CXCL9 and CXCL10 are the non-specific action immunomodulators that are responsible for ...
Chen Xu +6 more
doaj +1 more source
Медицинская иммунология, 2021 Atopic dermatitis is one of the most common chronic inflammatory skin diseases caused by both terminal defects in keratinocyte differentiation, and pronounced type 2 immune responses.
M. B. Drozhdina, E. V. Suslova
doaj +1 more source
CXCR3 chemokine receptor ligands in sarcoidosis
Медицинская иммунология, 2021 Sarcoidosis is a polysystemic inflammatory disease of unknown etiology, morphologically related to the group of granulomatosis, with heterogeneous clinical manifestations and outcomes.
N. M. Lazareva +7 more
doaj +1 more source
CXCR3-CXCL9: It’s All in the Tumor [PDF]
Immunity, 2019 In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.
Etienne, Humblin, Alice O, Kamphorst
openaire +2 more sources
Frontiers in Oncology, 2023 BackgroundThe C-X-C motif chemokine ligand-9 (CXCL9) is related to the progression of multiple neoplasms. Yet, its biological functions in uterine corpus endometrioid carcinoma (UCEC) remain shrouded in confusion.
Shen Xue +3 more
doaj +1 more source
Assessment of Serum Level of CXCL9 and CXCL10 in Cutaneous versus Systemic Lupus Erythematosus [PDF]
Al-Azhar International Medical Journal, 2021 Introduction: Lupus erythematosus has been a chronic inflammatory illness where chemokines play a great role in its pathogenesis. CXCL9 and CXCL10 are chemokines that were researched in a variety of inflammatory skin disorders for their crucial role in ...
Ghada Omar +4 more
doaj +1 more source
The CARDS toxin of Mycoplasma pneumoniae induces a positive feedback loop of type 1 immune response
Frontiers in Immunology, 2022 BackgroundWithin the past 3-5 years, Mycoplasma pneumoniae has become a major pathogen of community-acquired pneumonia in children. The pathogenic mechanisms involved in M.
Ting Wang +11 more
doaj +1 more source
The Role of MIG/CXCL9 in Cardiac Allograft Vasculopathy [PDF]
The American Journal of Pathology, 2002 T lymphocytes play a critical role in chronic rejection of transplanted hearts, or cardiac allograft vasculopathy (CAV). However, the molecular mediators of T lymphocyte recruitment in CAV are incompletely defined. We hypothesized that the chemokine, monokine induced by interferon-gamma (MIG/CXCL9), which induces T lymphocyte migration in vitro ...
James J, Yun +10 more
openaire +2 more sources