Results 71 to 80 of about 34,241 (258)
Dose dependent killing of S. pyogenes killing by CXCL9 and the SpeB generated fragment.
, 2013 The purified 18–73 SpeB generated CXCL9 fragment was compared to the intact CXCL9 for killing of S. pyogenes strain AP1. Curves represent mean bacterial killing in percent with standard error determined from at least three independent experiments. Inset:
Manisha Yadav (241190) +6 more
core +1 more source
Advanced Science, EarlyView.ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li +8 more
wiley +1 more source
Stem Cell Research & Therapy, 2018 Background Mesenchymal stem cells (MSCs) are known to home to injured and inflamed regions via the bloodstream to assist in tissue regeneration in response to signals of cellular damage.
Yu-Chien Guo +3 more
doaj +1 more source
CXCL9 is trimmed amino-terminally and carboxy-terminally by SpeB.
, 2013 Panel A: SpeB-processed CXCL9 was analyzed by MALDI-TOF mass spectroscopy. Masses in Dalton are indicated above the to main intensity peaks. Panel B: The primary sequence of mature CXCL9 with the proposed SpeB-generated fragment constituting amino acids ...
Manisha Yadav (241190) +6 more
core +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Molecular Pain, 2018 Chemokines-mediated neuroinflammation in the spinal cord plays a critical role in the pathogenesis of neuropathic pain. Chemokine CXCL9, CXCL10, and CXCL11 have been identified as a same subfamily chemokine which bind to CXC chemokine receptor 3 to exert
Xiao-Bo Wu +6 more
doaj +1 more source
Advanced Science, EarlyView.Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source
CXCL9 contributes to antimicrobial protection of the gut during citrobacter rodentium infection independent of chemokine-receptor signaling. [PDF]
PLoS Pathogens, 2015 Chemokines have been shown to be effective bactericidal molecules against a variety of bacteria and fungi in vitro. These direct antimicrobial effects are independent of their chemotactic activities involving immunological receptors.
Sarah A Reid-Yu +4 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen +7 more
wiley +1 more source
CXCL9 and CXCL10 are differentially associated with systemic organ involvement and pulmonary disease severity in sarcoidosis [PDF]
, 2020 BackgroundSarcoidosis is a granulomatous inflammatory disease with limited blood markers to predict outcomes. The interferon-gamma (IFN-γ)-inducible chemotactic cytokines (chemokines), CXCL9 and CXCL10, are both increased in sarcoidosis patients, yet ...
Koth, Laura L +17 more
core +1 more source