Results 151 to 160 of about 94,110 (297)
, 2017 Xiaoming Liu, Hongjun Liu, Lihua Dai, Bingjie Ma, Ke Ma Pain Management Center, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People’s Republic of China Objective: Chemokine CXCL12 and its ...
Liu X, Liu H, Dai L, Ma K, Ma BJ
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_In vivo_ photoacoustic molecular imaging with simultaneous multiple selective targeting using antibody-conjugated gold nanorods [PDF]
, 2008 The use of gold nanorods for photoacoustic molecular imaging in vivo with simultaneous multiple selective targeting is reported. The extravasation of multiple molecular probes is demonstrated, and used to probe molecular information of cancer cells. This
Ya-Na Wu +8 more
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Journal of Clinical Laboratory Analysis, EarlyView.Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li +3 more
wiley +1 more source
Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives
JSFA reports, EarlyView.Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz +10 more
wiley +1 more source
Multiomics Insights Into AL Amyloidosis
Medicine Bulletin, EarlyView.ABSTRACT Light chain amyloidosis is a systemic or localized protein conformational disorder triggered by misfolded immunoglobulin light chains, leading to amyloid fibril deposition. The disease is characterized by multiorgan involvement and delayed diagnosis, contributing to poor prognosis and high mortality rates.
Zixuan Zhang +6 more
wiley +1 more source
, 2015 Changyuan Zhang,1,* Jie Li,2,* Yi Han,3 Jian Jiang4 1Department of Cardiothoracic Surgery, Inner Mongolia Autonomous Region People’s Hospital, Inner Mongolia; 2Department of Oncology, 3Department of Thoracic Surgery, Beijing Chest Hospital ...
Jiang J, Li J, Han Y, Zhang C
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Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury
Neuroprotection, EarlyView.This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla +8 more
wiley +1 more source
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To investigate the role of TNF receptor‐associated factor 6 (TRAF6), interleukin 1 receptor‐associated kinase 1 (IRAK1), and miR‐146a‐5p expression levels in the pathogenesis of recurrent tonsillitis. Study Design Case‐control study. Setting The study was conducted at the Department of Otorhinolaryngology, Muğla Training and Research
Ömer Faruk Güzel +3 more
wiley +1 more source
The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski +7 more
wiley +1 more source
, 2015 Qi Chen, Tie Zhong Department of Urology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xian, Shaanxi Province, People’s Republic of China Abstract: CXCR4/CXCL12 axis plays an important role in tumor growth, angiogenesis ...
Chen Q, Zhong T
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