Results 151 to 160 of about 88,749 (308)
Gut and Liver, 2014 Background/AimsTo evaluate the expression of CXC motif chemokine receptor 4 (CXCR4) in the tissues of patients with hilar cholangiocarcinoma (hilar-CCA) and to investigate the cell proliferation and frequency of neural invasion (NI) influenced by RNAi ...
doaj +1 more source
The CXCR4/SDF1 axis improves muscle regeneration through MMP-10 activity
, 2014 The CXCR4/SDF1 axis participates in various cellular processes, including cell migration, which is essential for skeletal muscle repair. Although increasing evidence has confirmed the role of CXCR4/SDF1 in embryonic muscle development, the function of ...
Orbe, Josune [0000-0001-6300-7670] +7 more
core +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
NFAT3 regulates CXCR4 expression.
, 2014 HeyA8 cells were cultured as a monolayer (adherent) and as 3D spheroids as described in materials and methods. HeyA8 adherent cells were treated with calcineurin-NFAT inhibitor cyclosporin A (1 µM) andFK506 (3 µM) for 72 hours.
Keven Huang (675616) +2 more
core +1 more source
Interdisciplinary Medicine, EarlyView.Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi +18 more
wiley +1 more source
Effect of hydrogen peroxide on CXCR4 transcript levels after traumatic sciatic nerve injury
reservedIl sistema nervoso periferico, a differenza di quello centrale, ha un'intrinseca capacità di rigenerare in seguito a danno. Il recupero dipende sia da proprietà intrinseche dei neuroni periferici che dal microambiente cellulare, di cui sono ...
DI GIAMBATTISTA, SOFIA
core
Intracellular CXCR4+ cell targeting with T22-empowered protein-only nanoparticles
, 2012 Ugutz Unzueta,1–3 María Virtudes Céspedes,3,4 Neus Ferrer-Miralles,1–3 Isolda Casanova,3,4 Juan Cedano,5 José Luis Corchero,1–3 Joan Domingo-Espín,1–3 Antonio Villaverde ...
Corchero JL +9 more
core
Journal of Clinical Laboratory Analysis, EarlyView.Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li +3 more
wiley +1 more source
Reconceptualizing Aplastic Anemia—Seed, Worm, Soil
Journal of Clinical Laboratory Analysis, EarlyView.Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu +4 more
wiley +1 more source
Significance of CXCL12/CXCR4 Ligand/Receptor Axis in Various Aspects of Acute Myeloid Leukemia
Cancer Management and Research, 2020 Zinat Yazdani,1 Zahra Mousavi,2 Alireza Moradabadi,1 Gholamhossein Hassanshahi1,3 1Department of Hematology and Blood Banking, Kerman University of Medical Sciences, Kerman, Iran; 2Department of Hematology and Medical Laboratory Sciences, Iranshahr ...
Yazdani Z +3 more
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