Results 141 to 150 of about 88,749 (308)
Immune-cell-derived membranes have garnered significant attention as innovative delivery modalities in cancer immunotherapy for their intrinsic immune-modulating functionalities and superior biocompatibilities.
Yujin Kim (483088) +7 more
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
CXCR4-MLNR heteromerization modulates signaling and function of CXCR4
, 2021 학위논문 (석사) -- 서울대학교 대학원 : 자연과학대학 생명과학부, 2021. 2. 허원기.C-X-C chemokine receptor type 4 (CXCR4)는 23종 이상의 암세포에서 발현되는 G protein-coupled receptor (GPCR)로 암의 진행 및 전이에 관여한다. 이에 따라 CXCR4를 조절하기 위해 다양한 기초, 중개, 임상적인 시도들이 있었다.
김미나
core
Clinical Pharmacology &Therapeutics, EarlyView.Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović +11 more
wiley +1 more source
Chemokine receptor 4 (CXCR4) is part of the lipopolysaccharide "sensing apparatus"
, 2008 Recognition of bacterial lipopolysaccharide (LPS) by the innate immune system involves at least three receptor molecules: CD14, TLR4 and MD-2. Additional receptor components such as heat shock proteins, chemokine receptor 4 (CXCR4), or CD55 have been ...
Ahmed, Mohamed Abd Elrahman +16 more
core +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
, 2012 Fatemeh Abedini,1 Hossein Hosseinkhani,2 Maznah Ismail,1,3 Abraham J Domb,4 Abdul Rahman Omar,1,5 Pei Pei Chong,1,2 Po-Da Hong,3 Dah-Shyong Yu,6 Ira-Yudovin Farber41Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra Malaysia ...
Abedini F +8 more
core
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A novel graphene‐based broad‐spectrum infrared (BSIR) device is developed for the noninvasive treatment of ulcerative colitis (UC). BSIR irradiation effectively alleviates colonic inflammation and accelerates mucosal recovery by inducing the systemic relocation of T lymphocytes to the spleen.
Siyu Chen +15 more
wiley +1 more source
Clinicopathological significance of CXCR4 in non-small cell lung cancer
, 2015 Xiao-ming Zhou,1 Lan He,2 Gang Hou,3 Bing Jiang,4 Yuan-he Wang,5 Li Zhao1 1Department of Respiratory Medicine, The Shengjing Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Microbiology, The ...
Zhao L +5 more
core
Equine Veterinary Journal, EarlyView.Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
wiley +1 more source