Results 201 to 210 of about 142,759 (329)

CXCR4-modification enhances CAR-T efficacy by improving tumor tracking and bone marrow homing in B-cell malignancies. [PDF]

Signal Transduct Target Ther
Shu P, Guo F, Qin D, Zou L, Ma Q, Zhang B, Gao G, Chen Y, He X, Jiang M, Liu N, Zhou K, Zhao J, Lei Y, Gao Y, Zhang Y, Zeng Y, Feng M, Li X, Li D, Wang Y.   +20 more
europepmc   +1 more source

CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4 [PDF]

, 2006
Thomas Slagsvold, Adriano Marchese, Andreas Brech, Harald Stenmark   +3 more
openalex   +1 more source

Supplementary Figure 6 from SLITs Suppress Tumor Growth <i>In vivo</i> by Silencing <i>Sdf1/Cxcr4</i> within Breast Epithelium

, 2023
Rebecca Marlow, Phyllis Strickland, Ji Shin Lee, Xin‐Yan Wu, Milana PeBenito, Mikhail Binnewies, Elizabeth K. Le, Angel Moran, Hector Macias, Robert D. Cardiff, Saraswati Sukumar, Lindsay Hinck   +11 more
openalex   +1 more source

Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang, Zhiqin Fang, Lam C. Tsoi, Johann E. Gudjonsson   +3 more
wiley   +1 more source

CXCR4 induces memory formation over exhaustion in CAR-T cells to achieve durable leukemia targeting. [PDF]

Nat Commun
Itoh-Nakadai A, Liang M, Shindo M, Bibi C, Tomizawa-Murasawa M, Fujiki S, Kaneko A, Kanamaru E, Hashimoto M, Kajita H, Ando Y, Kojima M, Moody J, Iwasaki M, Takagi S, Nakagawa R, Agrawal S, Amitani-Iijima H, Sato K, Sorimachi Y, Suzuki N, Fukami T, Hanada K, Morita S, Katsura K, Matsumoto T, Kobayashi M, Kato M, Negishi Y, Shirouzu M, Najima Y, Takubo K, Hon CC, Uchida N, Taniguchi S, Momozawa Y, Carninci P, Shultz LD, Saito Y, de Hoon M, Shin JW, Ishikawa F.   +41 more
europepmc   +1 more source

Development of Stem-Cell-Mobilizing Agents Targeting CXCR4 Receptor for Peripheral Blood Stem Cell Transplantation and Beyond

, 2018
Chien-Huang Wu, Jen‐Shin Song, Hsuan-Hao Kuan, Szu‐Huei Wu, Ming‐Chen Chou, Jiing‐Jyh Jan, Lun K. Tsou, Yi‐Yu Ke, Chiung‐Tong Chen, Kai‐Chia Yeh, Sing-Yi Wang, Teng‐Kuang Yeh, Chen‐Tso Tseng, Chen‐Lung Huang, Mine-Hsine Wu, Po‐Chu Kuo, Chia‐Jui Lee, Kak‐Shan Shia   +17 more
openalex   +1 more source

The Influence of Tumor-Host Interactions in the Stromal Cell-Derived Factor-1/CXCR4 Ligand/Receptor Axis in Determining Metastatic Risk in Breast Cancer [PDF]

, 2009
Saima Hassan, Cristiano Ferrario, Uri Saragovi, Louise Quenneville, Louis Gaboury, Andrea Baccarelli, Ombretta Salvucci, Mark Basik   +7 more
openalex   +1 more source

Prognostic Significance of the Pretreatment Neutrophil‐to‐Lymphocyte Ratio and Tumor‐Associated Neutrophils in Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives The prognostic significance of the neutrophil‐to‐lymphocyte ratio (NLR) and tumor‐associated neutrophils (TANs) in head and neck squamous cell carcinoma (HNSCC) remains a subject of considerable research interest. This systematic review and meta‐analysis aimed to evaluate the relationship between pretreatment NLR and TANs and ...
Ahana Kapuge Dona Varuni Yashodha Ratnayake, Aini Hyytiäinen, Georgia Vasiliki Gkountana, Meri Torri, Ahmed Al‐Samadi   +4 more
wiley   +1 more source

G-CSF promotes H3K27ac-modified KLF5 to activate CXCR4 expression and drive colon cancer growth and metastasis. [PDF]

Eur J Med Res
Ma G, Jiang J, He T, Jin C, Wu W, Fan W, Wang T, Zhou P.   +7 more
europepmc   +1 more source

eLife assessment: Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain

Michael L. Dustin
openalex   +1 more source