Results 281 to 290 of about 88,749 (308)

Cloning of a CXCR4 homolog in chondrostean fish and characterization of the CXCR4-specific structural features

Developmental & Comparative Immunology, 2000
The chemokine receptor CXCR4 and its ligand SDF-1 are essential components of hematopoiesis, organogenesis and immunomodulation in mammalian species. We cloned a cDNA encoding CXCR4 homolog of sterlet (Acipenser ruthenus), a representative of chondrostean fishes.
B Y, Alabyev, A M, Najakshin, L V, Mechetina, A V, Taranin   +3 more
openaire   +2 more sources

CXCR4: chemokine receptor extraordinaire

Immunological Reviews, 2000
Current investigations show that chemokine receptor CXCR4 is functionally expressed on a multitude of tissues and cell types, including different leukocyte subsets, hematopoietic progenitor cells and non-hematopoietic cells such as endothelial and epithelial cells.
openaire   +2 more sources

HIV coreceptor CXCR4 antagonists

Current Opinion in HIV and AIDS, 2006
Increases in HIV resistance towards approved antiviral drugs have made it necessary to develop new and potent antiviral drugs with preferably a novel mode of action.Entry inhibitors constitute a new class of drugs to treat infection by HIV-1. The first member of this class, enfuvirtide, previously known as T-20 and targeting gp41, has now been licensed
openaire   +2 more sources

CXCR4 Imaging in Multiple Myeloma

2019
The C–X–C chemokine receptor 4 (CXCR4) and its natural ligand CXCL12 are key factors in the process of cell migration, homing of hematopoietic stem cells to the bone marrow, and represent important mediators of angiogenesis and cell proliferation. In many pathological conditions, such as multiple myeloma, high CXCR4 expression is frequently observed ...
Morales, M. I., Lapa, Constantin, Buck, A. K.   +2 more
openaire   +1 more source

CMTM4 is a novel interactor of CXCR4 and regulator of CXCL12/CXCR4 signaling

Ο CXCR4 είναι ένας υποδοχέας χημειοκινών που ανήκει στην υπεροικογένεια των υποδοχέων που συνδέονται με τις πρωτεΐνες G (G protein-coupled receptors). Ο φυσικός συνδέτης του CXCR4 είναι η χημειοκίνη CXCL12. Η αλληλεπίδραση μεταξύ του υποδοχέα και του συνδέτη του ενεργοποιεί πολυάριθμα σηματοδοτικά μονοπάτια, ελέγχοντας τη μετανάστευση, την επιβίωση ...
openaire   +1 more source

CXCR4, Coreceptors

2013
Ester Ballana, José A. Esté
openaire   +1 more source

Cell Membrane Vesicles with Enriched CXCR4 Display Enhances Their Targeted Delivery as Drug Carriers to Inflammatory Sites

Advanced Science, 2021
Dandan Wang, Boon Chin Heng, Yuanyuan Wang   +2 more
exaly  

CXCR4 Antagonists

2011
Klaus Dembowsky, Barbara Romagnoli, Johann Zimmermann, Eric Chevalier, Christian Ludin, Daniel Obrecht   +5 more
openaire   +1 more source

CXCR4 and Cancer

2009
Bungo Furusato, Johng S. Rhim
openaire   +1 more source

Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity

Circulation, 2017
Yvonne Döring, Heidi Noels, Emiel P C Van Der Vorst   +2 more
exaly