Results 11 to 20 of about 13,509,513 (296)

Identification of Cyclic-di-GMP-Modulating Protein Residues by Bidirectionally Evolving a Social Behavior in Pseudomonas fluorescens [PDF]

mSystems, 2022
Modulation of the intracellular cyclic di-GMP (c-di-GMP) pool is central to the formation of structured bacterial communities. Genome annotations predict the presence of dozens of conserved c-di-GMP catalytic enzymes in many bacterial species, but the ...
Collin Kessler, Wook Kim
doaj   +2 more sources

Roles of divalent metals in the regulation of cyclic di-GMP signaling in bacteria [PDF]

Journal of Bacteriology
Metals are essential co-factors that are important for the activity of many enzymes and, hence, bacterial life itself. Cyclic di-GMP (c-di-GMP) is an important signaling molecule that is prevalent across various bacterial phyla and involved in myriad ...
Aathmaja Anandhi Rangarajan, Christopher M. Waters   +1 more
doaj   +2 more sources

Measuring Individual Cell Cyclic di-GMP: Identifying Population Diversity and Cyclic di-GMP Heterogeneity

, 2020
Cyclic di-GMP is a second messenger used by bacteria to regulate motility, extracellular polysaccharide production, and the cell cycle. Recent advances in the measurement of real time cyclic di-GMP levels in single cells have uncovered significant dynamic heterogeneity of second messenger concentrations within bacterial populations.
Miller, Samuel I., Petersen, Erik
openaire   +3 more sources

Effects of the signaling molecule cyclic-di-GMP on cyanobacterial circadian rhythm in Synechococcus elongatus PCC 7942 [PDF]

Journal of Bacteriology
In phototrophic cyanobacteria, the signaling molecule bis-(3′-5′)-cyclic dimeric-guanosine monophosphate (c-di-GMP) plays important roles in a wide variety of functions associated with environmental conditions, including biofilm formation, motility ...
Chihiro C. Yamaguchi, Robert A. Kanaly, Eri Nishizaki, Keiichi Yamashita, Koichiro Takatsuki, Yoshihiko Furuike, Mingxu Fang, Shuji Akiyama, Setsuyuki Aoki, Masaki Tsukamoto, Yoichi Nakahira, Susan S. Golden, Shinsuke Kutsuna   +12 more
doaj   +2 more sources

Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP [PDF]

ACS Chemical Biology, 2018
Bacteria colonize highly diverse and complex environments, from gastrointestinal tracts to soil and plant surfaces. This colonization process is controlled in part by the intracellular signal cyclic di-GMP, which regulates bacterial motility and biofilm formation.
Andrew B. Dippel, Wyatt A. Anderson, Robert S. Evans, Samuel Deutsch, Ming C. Hammond   +4 more
openaire   +5 more sources

Discovery of the Second Messenger Cyclic di-GMP [PDF]

, 2017
The nearly ubiquitous bacterial second messenger cyclic di-GMP is involved in a multitude of fundamental physiological processes such as sessility/motility transition and the switch between the acute and chronic infection status, combined with cell cycle control.
Ute, Römling, Michael Y, Galperin
openaire   +3 more sources

Mechanisms of cyclic-di-GMP signaling : insight into the biochemistry, signal transduction and regulation of the bacterial second messenger cyclic-di-GMP [PDF]

, 2007
Bacteria are able to switch between two mutually exclusive lifestyles, motile single cells and sedentary multicellular communities that colonize surfaces. These behavioral changes contribute to an increased fitness in structured environments and are controlled by the ubiquitous bacterial second messenger c-di-GMP.
Christen, Matthias
openaire   +3 more sources

Lsr2 acts as a cyclic di-GMP receptor that promotes keto-mycolic acid synthesis and biofilm formation in mycobacteria [PDF]

Nature Communications
Cyclic di-GMP (c-di-GMP) is a second messenger that promotes biofilm formation in several bacterial species, but the mechanisms are often unclear. Here, we report that c-di-GMP promotes biofilm formation in mycobacteria in a manner dependent on the ...
Xiaocui Ling, Xiao Liu, Kun Wang, Minhao Guo, Yanzhe Ou, Danting Li, Yulin Xiang, Jiachen Zheng, Lihua Hu, Hongyun Zhang, Weihui Li   +10 more
doaj   +2 more sources

Cyclic di-GMP signalling and the regulation of bacterial virulence

Microbiology, 2013
Signal transduction pathways involving the second messenger cyclic di-GMP [bis-(3'-5')-cyclic di-guanosine monophosphate] occur widely in bacteria where they act to link perception of environmental or intracellular cues and signals to specific alterations in cellular function. Such alterations can contribute to bacterial lifestyle transitions including
Ryan, Robert P.
openaire   +4 more sources

Regulation by Cyclic di-GMP in Myxococcus xanthus

, 2020
Myxococcus xanthus has a complex lifecycle that is regulated by nutrient availability. In the presence of nutrients, M. xanthus cells grow, divide, and move to assemble into colonies that feed cooperatively either saprophytically or on prey. In response to starvation, a developmental program is initiated that culminates in formation of multicellular ...
María Pérez-Burgos, Lotte Søgaard-Andersen   +1 more
openaire   +2 more sources