Results 41 to 50 of about 13,048,753 (296)
PLoS ONE, 2013 The STING (stimulator of interferon genes) protein can bind cyclic dinucleotides to activate the production of type I interferons and inflammatory cytokines.
Guanghui Yi +5 more
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The regulation of alginate biosynthesis via cyclic di-GMP signaling
, 2020 Bacterial alginates are anionic exopolysaccharides, which are produced by Pseudomonas and Azotobacter species. Bacterial cells embedded in extracellular polymeric substances such as alginates have a survival advantage as they are protected against ...
Rehm, BHA, Moradali, MF
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Tracking the homeostasis of second messenger cyclic-di-GMP in bacteria [PDF]
Biophysical Reviews, 2020 Cyclic-di-GMP (c-di-GMP) is an important second messenger in bacteria which regulates the bacterial transition from motile to sessile phase and also plays a major role in processes such as cell division, exopolysaccharide synthesis, and biofilm formation. Due to its crucial role in dictating the bacterial phenotype, the synthesis and hydrolysis of c-di-
Anushya Petchiappan +2 more
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Principles of c-di-GMP signaling : characterization of a second messenger system orchestrating bacterial life style [PDF]
, 2007 Bacteria are able to switch between two mutually exclusive lifestyles, motile single cells and sedentary multicellular communities, known as biofilms, that colonize surfaces.
Christen, Beat
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Structural biology of bacterial response regulator proteins and their complexes with cognate ligands [PDF]
, 2009 Two bacterial response regulator systems were studied in this thesis. NMR spectroscopy and X-ray crystallography were used to determine the structures of both domains of the antibiotic sensor TipAL, as well as of the c-di-GMP receptor PA4608, in ...
Allan, Martin Georg
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The HD-GYP Domain, Cyclic Di-GMP Signaling, and Bacterial Virulence to Plants
Molecular Plant-Microbe Interactions, 2006 Cyclic di-GMP is an almost ubiquitous second messenger in bacteria that was first described as an allosteric activator of cellulose synthase but is now known to regulate a range of functions, including virulence in human and animal pathogens. Two protein
J. Maxwell Dow +3 more
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Shining the Light on Cyclic di-GMP Dark Matter [PDF]
Journal of Bacteriology, 2018 ABSTRACT Bacterial cyclic di-GMP signaling networks often consist of dozens of components, and the majority of these components have no observable function. Dahlstrom et al. (J. Bacteriol. 200:e00703-17, 2018, https://doi.org/10.1128/JB.00703-17 ) explored the function of every component of the
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, 2022 Pseudomonas aeruginosa is a Gram-negative bacterium that is able to survive and adapt in a multitude of niches as well as thrive within many different hosts. This versatility lies within its large genome of ca. 6 Mbp and a tight control in the expression
Joey Kuok Hoong Yam (6295388) +9 more
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Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides
Journal of Oral Microbiology, 2019 Background: Cyclic dinucleotides (cyclic di-guanosine monophosphate (c-di-GMP) and cyclic di-adenosine monophosphate (c-di-AMP)) and lipopolysaccharides (LPS) are pathogen-associated molecular patterns (PAMPs).
Samira Elmanfi +5 more
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Extraction and Quantification of Cyclic Di-GMP from Pseudomonas aeruginosa
Bio-Protocol, 2013 Cyclic di-GMP (c-di-GMP) has emerged as an important intracellular signaling molecule, controlling the transitions between planktonic (free-living) and sessile lifestyles, biofilm formation, and virulence in a wide variety of microorganisms.
Ankita Roy, Olga Petrova, Karin Sauer
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