Results 31 to 40 of about 13,509,513 (296)

Cyclic‐di‐GMP regulation of virulence in bacterial pathogens [PDF]

WIREs RNA, 2017
Signaling pathways allow bacteria to adapt to changing environments. For pathogenic bacteria, signaling pathways allow for timely expression of virulence factors and the repression of antivirulence factors within the mammalian host. As the bacteria exit the mammalian host, signaling pathways enable the expression of factors promoting survival in the ...
Cherisse L, Hall, Vincent T, Lee
openaire   +2 more sources

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]

, 2016
Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Fucile, Geoffrey, Dubey, Badri N., Ozaki, Shogo, Schirmer, Tilman, Lori, Christian, Jenal, Urs, Plaza-Menacho, Ivan, Fucile G, Lori, Christian (author), Ozaki S, Plaza-Menacho I, Fucile, Geoffrey (author), Dubey, Badri N. (author), Schirmer T, Plaza-Menacho, Ivan (author), Dubey BN, Jenal U, Jenal, Urs (author), Schirmer, Tilman (author), Lori C, Ozaki, Shogo (author)   +20 more
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Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]

, 2013
Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
core   +1 more source

A Cyclic Di-GMP Network Is Present in Gram-Positive Streptococcus and Gram-Negative Proteus Species [PDF]

, 2020
Cyclic di-GMP is a ubiquitous second messenger in bacteria. This work describes the occurrence of a cyclic di-GMP signaling network in Gram-positive Streptococcus species and Gram-negative Proteus.
Rey-Ting, Guo, Changhan, Lee, Heike, Bähre, Ute, Romling, Ying, Liu, Chun-Chi, Chen, Alexey, Chernobrovkin, Fengyang, Li, Janja, Trček, Roman, Zubarev, Liu, Y, Chun-Chi Chen, Li, F, Lee, C, Trček, J, Rey-Ting Guo, Fengyang Li, Janja Trček, Zubarev, R, Ying Liu, Romling, U, Heike Bähre, Changhan Lee, Roman Zubarev, Guo, R-T, Chernobrovkin, A, Alexey Chernobrovkin, Ute Romling, Bähre, H, Chen, C-C   +29 more
core   +1 more source

Insights into the activation mechanism of PopA, a cyclic di-GMP effector protein involved in cell cycle and development of "Caulobacter Crescentus" [PDF]

, 2012
In Caulobacter crescentus, a complex network integrating cyclic di-GMP and Phosphorylation-dependent signals controls the proteolysis of key regulatory proteins to drive cell cycle and polar morphogenesis.
Schalch-Moser, Annina Larissa
core   +1 more source

Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]

, 2013
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören, Bucher, Tabitha, Isabelle Hug (251572), Urs Jenal (37942), Isabelle Hug, Volkhard Kaever, Tabitha Bucher, Pia Abel zur Wiesch (353268), Jenal, U., Sören Abel, Bucher, T., Pia Abel Zur Wiesch, Micaël Nicollier, Micaël Nicollier (454806), Urs Jenal, Volkhard Kaever (152216), Hug, Isabelle, Tabitha Bucher (454805), Sören Abel (454804), Abel Zur Wiesch, P., Kaever, Volkhard, Hug, I., Abel zur Wiesch, Pia, Nicollier, M., Nicollier, Micaël, Abel, S., Jenal, Urs, Kaever, V., Sören Abel, Nicollier M, Abel S, Bucher T, Hug I, Jenal U, Kaever V, Abel Zur Wiesch P   +35 more
core   +2 more sources

A cyclic‐di‐GMP receptor required for bacterial exopolysaccharide production [PDF]

Molecular Microbiology, 2007
SummaryBis‐(3′,5′)‐cyclic‐dimeric‐guanosine monophosphate (c‐di‐GMP) has been shown to be a global regulatory molecule that modulates the reciprocal responses of bacteria to activate either virulence pathways or biofilm formation. The mechanism of c‐di‐GMP signal transduction, including recognition of c‐di‐GMP and subsequent phenotypic regulation ...
Lee, Vincent T., Matewish, Jody M, Kessler, Jennifer L, Hyodo, Mamoru, Hayakawa, Yoshihiro, Lory, Stephen   +5 more
openaire   +4 more sources

Folding of the transcription factor Brinker and interactions of the bacterial second messenger c-di-GMP studied by NMR [PDF]

, 2013
Nuclear magnetic resonance (NMR) spectroscopy is a technique, which allows the non-invasive investigation of structures, dynamics and interactions of biomolecules.
Gentner, Martin
core   +1 more source

STING is a direct innate immune sensor of cyclic di-GMP [PDF]

Nature, 2011
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial molecules. The recognition of microbial ligands leads to the production of cytokines, such as type I interferons (IFNs), that are essential for successful pathogen elimination. Cytosolic detection of pathogen-derived DNA is one major
Burdette, Dara L, Monroe, Kathryn M, Sotelo-Troha, Katia, Iwig, Jeff S, Eckert, Barbara, Hyodo, Mamoru, Hayakawa, Yoshihiro, Vance, Russell E   +7 more
openaire   +4 more sources

The exopolysaccharide gene cluster Bcam1330-Bcam1341 is involved in Burkholderia cenocepacia biofilm formation, and its expression is regulated by c-di-GMP and Bcam1349 [PDF]

, 2013
In Burkholderia cenocepacia, the second messenger cyclic diguanosine monophosphate (c-di-GMP) has previously been shown to positively regulate biofilm formation and the expression of cellulose and type-I fimbriae genes through binding to the ...
Ryan, Robert P, Givskov, Michael, Fazli, Mustafa, Tolker-Nielsen, Tim, McCarthy, Yvonne   +4 more
core   +1 more source