Results 71 to 80 of about 9,877,914 (299)

Fluorescent Detection of the Ubiquitous Bacterial Messenger 3′,5′ Cyclic Diguanylic Acid by Using a Small Aromatic Molecule

Frontiers in Microbiology, 2020
3′,5′ Cyclic diguanylic acid (c-di-GMP) has been shown to play a central role in the regulation of bacterial physiological processes such as biofilm formation and virulence production, and is regarded as a potential target for the development of anti ...
Teng-Fei Xuan, Jun Liu, Zi-Qiang Wang, Wei-Min Chen, Jing Lin   +4 more
doaj   +1 more source

Functional diversity of c-di-GMP receptors in prokaryotic and eukaryotic systems

Cell Communication and Signaling, 2023
Cyclic bis-(3', 5')-dimeric guanosine monophosphate (c-di-GMP) is ubiquitous in many bacterial species, where it functions as a nucleotide-based secondary messenger and is a vital regulator of numerous biological processes.
Fazlurrahman Khan, Geum-Jae Jeong, Nazia Tabassum, Young-Mog Kim   +3 more
doaj   +1 more source

Evidence for Cyclic Di-GMP-Mediated Signaling in Bacillus subtilis [PDF]

Journal of Bacteriology, 2012
ABSTRACTCyclic di-GMP (c-di-GMP) is a second messenger that regulates diverse cellular processes in bacteria, including motility, biofilm formation, cell-cell signaling, and host colonization. Studies of c-di-GMP signaling have chiefly focused on Gram-negative bacteria.
Yun, Chen, Yunrong, Chai, Jian-hua, Guo, Richard, Losick   +3 more
openaire   +2 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Riboswitches in Eubacteria Sense the Second Messenger Cyclic Di-GMP [PDF]

Science, 2008
Cyclic di-guanosine monophosphate (di-GMP) is a circular RNA dinucleotide that functions as a second messenger in diverse species of bacteria to trigger wide-ranging physiological changes, including cell differentiation, conversion between motile and biofilm lifestyles, and virulence gene expression.
N, Sudarsan, E R, Lee, Z, Weinberg, R H, Moy, J N, Kim, K H, Link, R R, Breaker   +6 more
openaire   +2 more sources

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Screening for Diguanylate Cyclase (DGC) Inhibitors Mitigating Bacterial Biofilm Formation

Frontiers in Chemistry, 2020
The majority of bacteria in the natural environment organize themselves into communal biofilms. Biofilm formation benefits bacteria conferring resistance to harmful molecules (e.g., antibiotics, disinfectants, and host immune factors) and coordinating ...
Kyu Hong Cho, R. Grant Tryon, Jeong-Ho Kim   +2 more
doaj   +1 more source

c-di-GMP inhibits the DNA binding activity of H-NS in Salmonella

Nature Communications, 2023
Cyclic di-GMP (c-di-GMP) is a second messenger that transduces extracellular stimuli into cellular responses and regulates various biological processes in bacteria. H-NS is a global regulatory protein that represses expression of many genes, but how H-NS
Shuyu Li, Qinmeng Liu, Chongyi Duan, Jialin Li, Hengxi Sun, Lei Xu, Qiao Yang, Yao Wang, Xihui Shen, Lei Zhang   +9 more
doaj   +1 more source

Structural elucidation of the multidomain response regulator PleD using X-ray crystallography [PDF]

, 2004
c-diGMP (bis-(3!5)-cyclic di-guanosine monophosphate) is used extensively in bacteria to control biofilm formation and is lately postulated as a novel secondary messenger.
Chan, Carmen
core   +1 more source