Results 261 to 270 of about 73,847 (309)

Cyclic Adenosine Monophosphate as a Mediator of Hormone Action

New England Journal of Medicine, 1971
ACCORDING to the classic definition, hormones are substances that are secreted by certain tissues and are carried by the circulation to other tissues, where their metabolic effects appear.
G W, Liddle, J G, Hardman
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Cyclic Adenosine Monophosphate and Hypertension in Rats

Science, 1973
Aortas from spontaneously hypertensive and stress hypertensive rats contained significantly lower intracellular concentrations of cyclic adenosine monophosphate than did their respective controls. Adenylate cyclase activity was normal but was less responsive to stimulation, while phosphodiesterase activity (especially the low Michaelis-Menten constant ...
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Cyclic Adenosine Monophosphate Stimulation of Axonal Elongation

Science, 1972
Elevated concentrations of adenosine 3′,5′-monophosphate induce a variety of cell movements. The role of adenosine 3′,5′-monophosphate in promoting those movements associated with growth prompted our study of in vitro microtubule-dependent axonal elongation.
F J, Roisen, R A, Murphy, M E, Pichichero, W G, Braden   +3 more
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Studies of the cyclic adenosine monophosphate chemoreceptor ofParamecium

The Journal of Membrane Biology, 1991
A doublet of proteins (approximately 48,000 Mr) from the Paramecium cell body membrane fits several criteria for the external cAMP chemoreceptor. These criteria include: (i) selective elution from a cAMP affinity column, matching a specificity that could be predicted from the behavioral response and whole-cell binding; (ii) binding to wheat germ ...
J L, Van Houten, B L, Cote, J, Zhang, J, Baez, M L, Gagnon   +4 more
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Modulation of Synapse Formation by Cyclic Adenosine Monophosphate

Science, 1983
Synapses between neuroblastoma-hybrid cells and myotubes exhibit a high degree of plasticity. Increase of cyclic adenosine monophosphate (AMP) levels of the hybrid cells for several days results in the appearance of functional voltage-sensitive Ca2+ channels, which are required for evoked secretion of acetylcholine.
M, Nirenberg, S, Wilson, H, Higashida, A, Rotter, K, Krueger, N, Busis, R, Ray, J G, Kenimer, M, Adler   +8 more
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Effects of adenosine 5′-monophosphate and adenosine 3′,5′-cyclic monophosphate on l cells

Journal of Cell Science, 1975
ABSTRACT The adenine nucleotides, 5′-AMP and 3′5′-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5′-AMP, and rates of uridine transport are increased after incubation with either 5′-AMP or cyclic AMP.
J, Taylor-Papadimitriou, T, Karemfyllis, A, Eukarpidou, G, Karamanlidou   +3 more
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Effect of Angiotensin II on Cyclic Guanosine Monophosphate and Cyclic Adenosine Monophosphate in Human Plasma

The Journal of Clinical Endocrinology & Metabolism, 1976
Infusion of alpha-adrenergic catecholamines increases plasma cyclic guanosine monophosphate (pcGMP), raising the possibility that the pressor effect of these agents may be mediated by cyclic GMP. We infused pressor doses of angiotensin II in 10 studies in 8 normal subject and measured pcGMP and plasma cyclic adenosine monophosphate (pcAMP) by ...
P M, Rosman, R, Agrawal, A D, Goodman, A L, Steiner   +3 more
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Hydrolysis of cyclic guanosine monophosphate and cyclic adenosine monophosphate by the penis and aorta of the diabetic rat

British Journal of Urology, 1996
Objective  To investigate the hydrolysis of adenosine 3′5′‐cyclic monophosphate (cAMP) and guanosine 3′5′‐cyclic monophosphate (cGMP) by specific phosphodiesterases (PDEs) in the penis and aorta of diabetic rats. Materials and methods
M A, Miller, R J, Morgan, C S, Thompson, D P, Mikhailidis, J Y, Jeremy   +4 more
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Cyclic Adenosine Monophosphate in Cerebral Cortex

Archives of Neurology, 1975
Stab-wound injury produced a seven-fold elevation in cyclic adenosine monophosphate (AMP) in mouse brain within one minute. The increase in cyclic AMP in the brain was blocked by prior treatment of the animal by theophylline, chlorpromazine, trifluoperazine hydrochloride, and diphenhydramine hydrochloride. Neither dichloroisoproterenol, pronetalol, nor
H, Watanabe, J V, Passonneau
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Determination of Cyclic Adenosine 3′,5′-Monophosphate in Urine

Scandinavian Journal of Clinical and Laboratory Investigation, 1976
A modification of Aurbach & Houston's enzymic method for measuring cAMP is presented. The procedure is relatively simple and in several respects new. Urinary cAMP is separated from other nucleotides and phosphate by ZnSO4-Ba(OH)2 precipitation and column chromatography. The eluate is concentrated by evaporation. Recovery at this stage is 60-82%.
K, Raij, M, Härkönen
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