Results 21 to 30 of about 121,650 (304)

c-di-AMP: An essential molecule in the signaling pathways that regulate the viability and virulence of gram-positive bacteria [PDF]

open access: yes, 2017
Signal transduction pathways enable organisms to monitor their external environment and adjust gene regulation to appropriately modify their cellular processes.
Cho, Kyu Hong   +2 more
core   +2 more sources

Cyclic AMP Accumulation in Migraine Induction

open access: yesPediatric Neurology Briefs, 2015
Investigators from Danish Headache Centre, Glostrup Hospital, and the University of Copenhagen investigated whether intracellular cyclic AMP accumulation induced migraine attacks among 14 migraine patients without aura.
Ana B Chelse, Leon G Epstein
doaj   +1 more source

Characterization of the taste receptor‐related G‐protein, α‐gustducin, in pancreatic β‐cells

open access: yesJournal of Diabetes Investigation, 2020
Aims/Introduction Taste receptors, T1rs and T2rs, and the taste‐selective G‐protein, α‐gustducin, are expressed outside the taste‐sensing system, such as enteroendocrine L cells.
Haruhide Udagawa   +7 more
doaj   +1 more source

The Relationship between Blood Thyroid Hormone and Dopamine Levels in Residents of the Arctic Regions of Russia [PDF]

open access: yesInternational Journal of Biomedicine, 2019
Due to the presence of contradictory results about the effect of dopamine on the synthesis and secretion of thyroid hormones, as well as the absence of this information in clinically healthy individuals, we were interested in studying this problem in ...
Elena V. Tipisova   +9 more
doaj   +1 more source

Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

open access: yesEuropean Journal of Histochemistry, 2012
In Dictyostelium discoideum (D. discoideum), compounds generating nitric oxide (NO) inhibit its aggregation and differentiation without altering cyclic guanosine monophosphate (cGMP) production.
A. Amaroli, M.G. Chessa
doaj   +1 more source

Liver hydrolysate improves depressive-like behavior in olfactory bulbectomized mice: Involvement of hippocampal neurogenesis through the AMPK/BDNF/CREB pathway

open access: yesJournal of Pharmacological Sciences, 2020
Recently, we has reported that AMPK activator has antidepressant effect. Previous our study suggested that liver hydrolysate (LH) activated adenosine monophosphate-activated protein kinase (AMPK) in periphery.
Osamu Nakagawasai   +8 more
doaj   +1 more source

Effects of cyclic nucleotides on midgut infections and maturation of T. b. brucei in G. m. morsitans

open access: yesParasites & Vectors, 2008
Cyclic nucleotide signalling through cyclic adenosine monophosphate (cAMP) is thought to play an important role in the transformation of the long slender (dividing) form to the short-stumpy (arrested) form in the mammalian bloodstream but the role of ...
Maudlin Ian   +2 more
doaj   +1 more source

The low KM-phosphodiesterase inhibitor denbufylline enhances neuronal excitability in guinea pig hippocampus in vitro [PDF]

open access: yes, 1990
The actions of the phosphodiesterase inhibitor denbufylline on the excitability of hippocampal neurons were investigated by means of extracellular and intracellular recordings.
Alzheimer, Christian   +3 more
core   +1 more source

Vinpocetine is the forthcoming adjuvant agent in the management of COVID-19

open access: yesFuture Science OA, 2022
Vinpocetine (VPN) is an alkaloid derivative of vincamine inhibits phosphodiesterase type 1 that increase cyclic guanosine monophosphate and cyclic adenosine monophosphate. VPN have anti-inflammatory and antioxidant effects with suppression release of pro-
Hayder M Al-kuraishy   +3 more
doaj   +1 more source

Cyclic AMP metabolism and adenylate cyclase concentration in patients with advanced hepatic cirrhosis [PDF]

open access: yes, 1978
Glucagon was tested for its effect on plasma adenosine 3′,5′-cyclic monophosphate (cyclic AMP), insulin, and glucose in healthy subjects and in patients with advanced cirrhosis of the liver. In the normal subjects, intravenous infusion of glucagon caused
Antonio Francavilla   +61 more
core   +1 more source

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