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Cyclic ADP-Ribose and Vasomotor Response

2002
Vascular smooth muscle (VSM) usually exists in a partially contracted state, from which it can contract further or relax in response to different physiological or pathological stimulations. This contracted state of blood vessels and their contracting and relaxing response to stimuli are often referred to as “vascular tone” and “vasomotor response ...
Pin-Lan Li   +2 more
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Cyclic ADP-Ribose: Metabolism and Calcium Mobilizing Function

1994
Publisher Summary This chapter describes the discovery of cyclic adenosine diphosphate–ribose (cADPR) as a novel endogenous Ca 2+ -mobilizing agent, and the way by which it fulfills most of the criteria necessary for it to be considered a second messenger. The enzymatic pathways for the synthesis and degradation of the metabolite are also summarized.
H C, Lee, A, Galione, T F, Walseth
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Cyclic ADP-Ribose and Calcium Signalling

1998
It is over 100 years since calcium was first implied as an intracellular regulator in heart by Ringer (1882). Since then its universal role as a regulator has become a cornerstone of cell physiology (Campbell 1983), and much progress has been made in our understanding of cellular calcium homeostasis and the way in which cellular stimuli are transduced ...
A. Galione, H. L. Wilson
openaire   +1 more source

Cyclic ADP-ribose and ABA signal transduction

Trends in Plant Science, 1998
A new assay system utilizing ABA-inducible gene expression in tomato hypocotyl cells has placed cADPR firmly in the signal transduction cascade of this hormone[1xAbscisic acid signaling through cyclic ADP-ribose in plants. Wu, Y. et al. Science. 1997; 278: 2126–2130Crossref | PubMed | Scopus (273)See all References][1].
Gethyn J. Allen, Julian I. Schroeder
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A Redox Role for Cyclic ADP-Ribose

Science's STKE, 2001
Hypoxic pulmonary vasoconstriction is a normal physiological response that coordinates pulmonary perfusion to respiratory ventilation. NADH (reduced nicotinamide adenine dinucleotide) is thought to have a role in pulmonary artery contraction.
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Bioorganic chemistry of cyclic ADP-ribose (cADPR).

Bioorganic & medicinal chemistry, 1999
The objective of this brief review is to present an overview of the bioorganic chemistry of cyclic-ADP-ribose (cADPR) with special emphasis on the methodology used for the synthesis of analogues of cADPR. New structural analogues of cADPR can be prepared using either the biomimetic method or ADP-ribosyl cyclase from Aplysia californica.
F J, Zhang, Q M, Gu, C J, Sih
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[27] Preparation of cyclic ADP-ribose antagonists and caged cyclic ADP-ribose

1997
Timothy F. Walseth   +6 more
openaire   +1 more source

Cyclic ADP-Ribose in β Cells

Science, 1993
Md. Shahidul Islam   +2 more
openaire   +1 more source

Cyclic ADP-ribose and NAADP

2003
Antony Galione, Grant C. Churchill
openaire   +1 more source

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