Genome-Wide Mapping Defines a Role for C/EBPβ and c-Jun in Non-Canonical Cyclic AMP Signalling
The novel exchange protein activated by cyclic AMP (EPAC1) activator, I942, induces expression of the suppressor of cytokine signalling 3 (SOCS3) gene, thereby inhibiting interleukin 6 (IL6) inflammatory processes in human umbilical vein endothelial ...
Jolanta Wiejak+3 more
doaj +1 more source
Characterization of the norepinephrine-activation of adenylate cyclase suggests a role in memory affirmation pathways. Overexposure to epinephrine inactivates adenylate-cyclase,a causal pathway for stress-pathologies [PDF]
Incubation with noradrenaline (norepinephrine) of isolated membranes of rat's brain corpus striatum and cortex, showed that ionic-magnesium (Mg2+) is required for the neurotransmitter activatory response of Adenylate Cyclase [ATP pyrophosphate-lyase (cyclizing), (EC 4.6.1.1)], AC.An Mg2+-dependent response to the activatory effects of adrenaline, and ...
arxiv
Isolation of Nuclei from Physarum flavicomum: Demonstration of Nuclear Cyclic Acid AMP Phosphodiesterase [PDF]
Cyclic AMP phosphodiesterase activity in the nucleus of the myxomycete Physarum flavicomum was demonstrated by cytochemical staining utilizing electron microscopy and by enzymatic assays with tritiated cyclic AMP as the substrate.
Bean, Judith A.+2 more
core +2 more sources
Regulation of the G2/M Transition in Rodent Oocytes [PDF]
Regulation of maturation in meiotically competent mammalian oocytes is a complex process involving the carefully coordinated exchange of signals between the somatic and germ cell compartments of the ovarian follicle via paracrine and cell–cell coupling ...
Downs, Stephen
core +2 more sources
From Damage to Functionality: Remanufacturing of Thrust Roller Bearings by Tailored Forming
Herein, the wear and fatigue behavior of repaired bearing raceways with a new powder alloy is investigated using a FE8 test‐rig and an oscillating tribometer. The tests are compared with industrial manufactured bearings to evaluate the repair quality. The repair can extend the service life of the repaired bearing to that of a new bearing and improves ...
Felix Saure+3 more
wiley +1 more source
Cyclic AMP dynamics in the pancreatic β-cell
Insulin secretion from pancreatic β-cells is tightly regulated by glucose and other nutrients, hormones, and neural factors. The exocytosis of insulin granules is triggered by an elevation of the cytoplasmic Ca2+ concentration ([Ca2+]i) and is further ...
A. Tengholm
semanticscholar +1 more source
Squares of matrix-product codes [PDF]
The component-wise or Schur product $C*C'$ of two linear error-correcting codes $C$ and $C'$ over certain finite field is the linear code spanned by all component-wise products of a codeword in $C$ with a codeword in $C'$.
Cascudo, Ignacio+2 more
core +3 more sources
Simulation of Inhomogeneous Refractive Index Fields Induced by Hot Tailored Forming Components
This article presents a simulation model for simulating inhomogeneous refractive index fields (IRIF) in hot‐forged components, accounting for thermal influences and complex geometries. Through this simulation, a priori knowledge about the propagation of the IRIF can be obtained, allowing for the positioning of the component or an optical measurement ...
Pascal Kern+3 more
wiley +1 more source
Cyclic AMP metabolism in adipose tissue of exercise-trained rats.
Cyclic AMP metabolism in epididymal adipose tissue of exercise-trained rats was examined to determine if training induced changes in cyclic AMP production or inactivation.
E W Askew+3 more
doaj
Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK). [PDF]
Madin-Darby canine kidney (MDCK) cells grown in tissue culture have the morphological properties of distal tubular epithelial cells, form tight junctions, and lack several proximal tubular enzyme markers.
Chuman, LM+3 more
core