Results 21 to 30 of about 251,702 (334)

Digital image processing of optical density wave propagation in Dictyostelium discoideum and analysis of the effects of caffeine and ammonia [PDF]

open access: yes, 1989
Waves of chemotactic movement during the early phase of aggregation in Dictyostelium discoideum were analyzed by digital image processing in a manner that immediately shows the following parameters: wave propagation velocity, period length, wave ...
Siegert, Florian, Weijer, Cornelis J.
core   +1 more source

RAS and beyond: the many faces of the neurofibromatosis type 1 protein

open access: yesDisease Models & Mechanisms, 2022
Neurofibromatosis type 1 is a rare neurogenetic syndrome, characterized by pigmentary abnormalities, learning and social deficits, and a predisposition for benign and malignant tumor formation caused by germline mutations in the NF1 gene.
Corina Anastasaki   +2 more
doaj   +1 more source

Relationship between cyclic AMP production and lipolysis induced by forskolin in rat fat cells.

open access: yesJournal of Lipid Research, 1992
Forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) induced both cyclic AMP production and lipolysis in intact fat cells, but stimulated lipolysis without increasing cyclic AMP at a concentration of 10(-5) M ...
H Okuda, C Morimoto, T Tsujita
doaj   +1 more source

Activation of hormone-sensitive lipase in extracts of adipose tissue

open access: yesJournal of Lipid Research, 1970
Rat adipose tissue was homogenized in 0.154 m KCI, and the supernatant fluid, obtained after centrifugation at 15,000 g, was extracted with benzene to remove triglycerides. Most of the lipase activity in the extracted fluid was precipitated with ammonium
SU-CHEN TSAI   +2 more
doaj   +1 more source

Ultrasonic controllable synthesis of sulfur-functionalized metal–organic frameworks (S-MOFs) and their application in piezo-photocatalytic rapid reduction of hexavalent chromium (Cr)

open access: yesUltrasonics Sonochemistry
The United Nations’ Sustainable Development Goals (SDGs) are significant in guiding modern scientific research. In recent years, scholars have paid much attention to MOFs materials as green materials.
Zhiwei Liu   +8 more
doaj   +1 more source

Short PDE4 Isoforms as Drug Targets in Disease

open access: yesFrontiers in Bioscience-Landmark, 2023
The second messenger, cyclic adenosine monophosphate (cAMP), is a master regulator of signal transduction that maintains cell homeostasis. A fine balance between cAMP synthesis by adenylyl cyclase and degradation by phosphodiesterases (PDEs) underpins ...
Elka Kyurkchieva, George S. Baillie
doaj   +1 more source

The Role of Cyclic AMP Signaling in Cardiac Fibrosis

open access: yesCells, 2019
Myocardial stress and injury invariably promote remodeling of the cardiac tissue, which is associated with cardiomyocyte death and development of fibrosis. The fibrotic process is initially triggered by the differentiation of resident cardiac fibroblasts
Marion Delaunay   +3 more
doaj   +1 more source

Regulation of the G2/M Transition in Rodent Oocytes [PDF]

open access: yes, 2010
Regulation of maturation in meiotically competent mammalian oocytes is a complex process involving the carefully coordinated exchange of signals between the somatic and germ cell compartments of the ovarian follicle via paracrine and cell–cell coupling ...
Downs, Stephen
core   +2 more sources

Liver regeneration in dogs: Morphologic and chemical changes [PDF]

open access: yes, 1978
Forty-four percent and 72% hepatectomy were carried out in dogs and the animals were sacrificed for biochemical and pathologic studies from 0.5 to 6 days later.
Antonio Francavilla   +34 more
core   +1 more source

Cyclic AMP

open access: yesAnnals of Surgery, 1976
Cyclic AMP is believed to be the intracellular agent which mediates the action of many hormones on their target cell. The mechanisms by which the nucleotide controls glycogen metabolism in liver and skeletal muscle seem to be firmly established. Data relevant to this area of research are selectively reviewed.
openaire   +3 more sources

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