Results 251 to 260 of about 32,383 (302)

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Recent advances in Mpox across innate immunity, evasion, and clinical outcomes. [PDF]

Commun Biol
Oh J, Chung YS, Lee S.
europepmc   +1 more source

cGAS-STING signaling: a therapeutic target in inflammatory bowel disease and related colorectal cancer. [PDF]

Front Immunol
Chen X, Tang X, Chen S, Ye Y, Mao F.
europepmc   +1 more source

Isoquercitrin induces melanogenesis in B16F10 melanoma cells and zebrafish via the p38 and PKA/CREB signaling pathways: an experimental study. [PDF]

J Yeungnam Med Sci
Lee JH, Ko YS, Eom YS, Kim SJ.
europepmc   +1 more source

Precision Exercise in Type 2 Diabetes Mellitus: Targeting Signaling Networks for Lipid Homeostasis. [PDF]

Metabolites
Tian T, Yu F, Liu X, Zeng X, Yue J, Bao S.   +5 more
europepmc   +1 more source

Follicle-Stimulating Hormone in Peripheral Metabolism: Novel Insights into Growth Regulation and Potential Applications in Boar Production. [PDF]

Animals (Basel)
Wang G, Han X, Wu, Zhuo Y.
europepmc   +1 more source

Cyclic AMP response element-binding protein and depression

Expert Review of Neurotherapeutics, 2002
Depression is one of the most common and most devastating psychiatric disorders. Although a variety of treatment strategies is available, a major problem in its therapy consists of the unpredictability of the drug response. Furthermore, most antidepressant drugs, which usually increase 5-HT and norepinephrine levels in the synaptic cleft, are likely to
Johannes, Thome, Fritz A, Henn, Ronald S, Duman   +2 more
openaire   +3 more sources

Isoforms of cyclic AMP response element binding proteins in Drosophila S2 cells

Biochemical and Biophysical Research Communications, 2004
Activation or inhibition of the cyclic AMP (cAMP)-protein kinase A (PKA) pathway can ultimately regulate the transcription of a variety of genes. In vertebrates, the best characterized nuclear targets of PKA are the 'cAMP response element' (CRE) binding proteins (CREB).
Jeroen, Poels, Vanessa, Franssens, Tom, Van Loy, Alberto, Martinez, Marie-Marthe, Suner, Stuart J, Dunbar, Arnold, De Loof, Jozef, Vanden Broeck   +7 more
openaire   +3 more sources

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Cyclic AMP response element-binding protein is required for normal maternal nurturing behavior

Neuroscience, 2005
Analysis of mice with targeted disruptions of fosB or the gene encoding dopamine beta-hydroxylase suggests that FosB and adrenergic signaling play critical roles in maternal nurturing behavior. The majority of neonates born to null females from either mutation fail to thrive, and virgin mutant females of both lines exhibit impaired pup retrieval ...
S-H, Jin, J A, Blendy, S A, Thomas
openaire   +4 more sources