Results 81 to 90 of about 433,171 (190)

Total Synthesis of the Antifungal Depsipeptide Petriellin A

, 2016
We report the solid-phase total synthesis of the antifungal highly modified cyclic depsipeptide petriellin A. The synthesis confirms earlier reports on the absolute configuration of the natural product.
Denis Scanlon (2175570), Andrew B. Hughes (2175572), John Karas (2175568), Marianne M. Sleebs (2175564), Rani Maharani (2175566)   +4 more
core   +1 more source

The mycotoxin definition reconsidered towards fungal cyclic depsipeptides

Journal of Environmental Science and Health, Part C, 2016
Currently, next to the major classes, cyclic depsipeptides beauvericin and enniatins are also positioned as mycotoxins. However, as there are hundreds more fungal cyclic depsipeptides already identified, should these not be considered as mycotoxins as well?
Lien, Taevernier, Evelien, Wynendaele, Leen, De Vreese, Christian, Burvenich, Bart, De Spiegeleer   +4 more
openaire   +2 more sources

Constitutive modelling of the behaviour of clays under cyclic loading [PDF]

, 1989
Includes bibliography.This research work involved the implementation of a constitutive model based on plasticity theory to model the behaviour of a clay under cyclic loading.
Sellers, E J
core   +1 more source

The role of the cyclic depsipeptide rings in antibiotics.

The Journal of Antibiotics, 1985
The physical and biological roles of the cyclic depsipeptides of actinomycin, quinomycin and triostin antibiotic families are proposed by examining the crystal structures of d(GC)-actinomycin D and d(CGTACG)-triostin A. The analyses suggest that not only are DNA-amino acid hydrogen-bonding and chromophore-base pair stacking crucially important for DNA ...
openaire   +3 more sources

Mechanistic insight into human androgen receptor-mediated endocrine disrupting potential of cyclic depsipeptide mycotoxin, beauvericin, and influencing environmental factors for its biosynthesis in Fusarium oxysporum KFCC 11363P on rice cereal

Ecotoxicology and Environmental Safety
In current study, Fusarium mycotoxin, beauvericin (BEA), has endocrine disrupting potential through suppressing the exogenous androgen receptor (AR)-mediated transcriptional activation.
Da-Hyun Jeong, Da-Woon Jung, Chaemin You, Hee-Seok Lee   +3 more
doaj   +1 more source

Total Synthesis of the Cyclic Depsipeptide Vioprolide D via its (Z)-Diastereoisomer. [PDF]

Angew Chem Int Ed Engl, 2020
Grab HA, Kirsch VC, Sieber SA, Bach T.
europepmc   +1 more source

Plitidepsin: design, development, and potential place in therapy

Drug Design, Development and Therapy, 2017
Sara Alonso-Álvarez,1 Emilia Pardal,2 Diego Sánchez-Nieto,3 Miguel Navarro,4 Maria Dolores Caballero,1 Maria Victoria Mateos,1 Alejandro Martín1 1Hematology Department, IBSAL-CIC-USAL, Hospital Universitario de Salamanca, Salamanca,
Alonso-Álvarez S, Pardal E, Sánchez-Nieto D, Navarro M, Caballero MD, Mateos MV, Martín A   +6 more
doaj  

Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking. [PDF]

J Nat Prod, 2020
Li Y, Yu HB, Zhang Y, Leao T, Glukhov E, Pierce ML, Zhang C, Kim H, Mao HH, Fang F, Cottrell GW, Murray TF, Gerwick L, Guan H, Gerwick WH.   +14 more
europepmc   +1 more source

Data from: Total Synthesis of the Cyclic Depsipeptide YM-280193, a Platelet Aggregation Inhibitor

Attached file provides supplementary data for linked article. The first total synthesis of YM-280193, a cyclic depsipeptide that inhibits the ADP-induced aggregation of human platelets, is described.

core  

Structural and functional studies of cyclic depsipeptide biosynthesis

, 2019
Cyclic depsipeptides, ubiquitous natural products of industrial and medical importance, are produced by nonribosomal peptide synthetases (NRPS) using a diverse repertoire of biosynthetic mechanisms.
Alonzo Muniz, Diego
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