Results 121 to 130 of about 1,254,991 (185)

Controlling production of brominated cyclic depsipeptides by Pseudoalteromonas maricaloris KMM 636T

Letters in Applied Microbiology, 2005
Aims: This study aims at evaluating the impact of the nutrient medium components on the in vitro production of the cytotoxic alterochromides. Methods and Results: The employment matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS ...
L S Shevchenko, M P Sobolevskaya, G B Elyakov   +2 more
exaly   +2 more sources

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The Cyclic Depsipeptide Backbone of the Didemnins

Acta Crystallographica Section C Crystal Structure Communications, 1995
An X-ray crystal analysis of phi-lactone N-¿1-¿N-¿4-¿[3- hydroxy-5-methyl-1-oxo-4-(N-L-threonylamino)heptyl]- oxy¿-2,5-dimethyl-1,3-dioxohexyl¿-L-leucyl¿-L-prolyl¿- N,O-dimethyl-L-tyrosine hydrobromide hydrate (1a), C42H66N5O11+.Br-.H2O, was obtained in order to determine the backbone folding of the macrocycle and to compare the results obtained with ...
S C, Mayer, P J, Carroll, M M, Joullié
openaire   +2 more sources

Mass spectra of cyclic depsipeptides: sporidesmolides

Tetrahedron Letters, 1964
J S Shannon
exaly   +2 more sources

Discovery of potent antiosteoporotic cyclic depsipeptides with an unusual nitrile hydroxy acid from Microascus croci.

Bioorganic chemistry (Print)
Two cyclic octadepsipeptides, microascusins A and B (1 and 2), were identified from the marine sponge-associated Microascus croci IMB19-064 co-cultivated with Escherichia coli.
Sha-Sha Li, Yi-Ning Li, Ting-Ting Yu, Xinwei Wei, Yu-Yan Zhang, Bo Chen, Shu-Yi Si, Yanni Xu, Maoluo Gan   +8 more
semanticscholar   +1 more source

Clavariopsins C-I, Antifungal Cyclic Depsipeptides from the Aquatic Hyphomycete Clavariopsis aquatica.

Journal of Natural Products, 2019
Seven new cyclic depsipeptides, clavariopsins C-I (3-9), together with two known congeners, clavariopsins A and B (1 and 2), were isolated from the aquatic hyphomycete Clavariopsis aquatica.
Thin Wut Soe, Chunguang Han, R. Fudou, Kenichi Kaida, Sawaki Yuki, Tomohiko Tomura, M. Ojika   +6 more
semanticscholar   +1 more source

Total Synthesis of the Marine Cyclic Depsipeptide Viequeamide A

Journal of Natural Products, 2013
The first total synthesis of viequeamide A, a natural cyclic depsipeptide isolated from a marine button cyanobacterium, was achieved with the N-Me-Val-Thr peptide bond as the final macrocyclization site. The synthetic product gave nearly identical spectroscopic data to that reported for the natural product.
Dongyu, Wang, Shanshan, Song, Ye, Tian, Youjun, Xu, Zehong, Miao, Ao, Zhang   +5 more
openaire   +2 more sources

Molecular Selectivity in the Binding of Alkali Metals, Alkaline Earth Metals, First-Row Transition Metals, and Lanthanides with Cyclic Depsipeptides.

Journal of Physical Chemistry B
Beauvericin (BEA) and enniatins (ENN) are cyclic hexadepsipeptide mycotoxins known for their ionophoric activities across cell membranes. While their ability to selectively bind alkali ions to form binary complexes has been studied, their interaction ...
Emmanuel Nkyaagye, Miranda N Limbach, Thanh D. Do   +2 more
semanticscholar   +1 more source

Synergistic action of a cyclic depsipeptide and piperazine on nematodes

Parasitology Research, 2000
The present study describes the synergistic effects of the cyclic depsipeptide BAY 44-4400 and piperazine in the treatment against the nematodes Trichinella spiralis, Heligmosomoides polygyrus, and Heterakis spumosa. The in vitro anthelmintic activity of a combination of the two compounds (1.7 motility units) against T.
F, Nicolay, A, Harder, G, von Samson-Himmelstjerna, H, Mehlhorn   +3 more
openaire   +2 more sources

Total synthesis of aureobasidin a, an antifungal cyclic depsipeptide

Chemistry Letters, 1993
Abstract A total synthesis of an antifungal cyclic depsipeptide aureobasidin A was first achieved mainly using PyBroP1) as a coupling reagent. The synthetic cyclized product was completely identical with the natural antibiotic in all respects. Some unexpected reactions due to N-methylamino acid were also described.
Toru Kurome, Kaoru Inami, Tetsuya Inoue, Katsushige Ikai, Kazutoh Takesako, Ikunoshin Kato, Tetsuo Shiba   +6 more
openaire   +1 more source

Natural cyclic depsipeptides and their analogs as potential antimicrobial candidates: mechanistic insight.

Bioorganic chemistry (Print)
Microorganisms such as bacteria, viruses, fungi, and parasites cause serious infections in humans. The misuse of antimicrobial treatments in humans, animals, and agriculture has led to the development of resistant pathogens that can survive and multiply ...
Gautam Kumar, Kritika Engle
semanticscholar   +1 more source