Results 101 to 110 of about 497 (160)

Viequeamide A, a Cytotoxic Member of the Kulolide Superfamily of Cyclic Depsipeptides from a Marine Button Cyanobacterium

open access: yes, 2016
The viequeamides, a family of 2,2-dimethyl-3-hydroxy-7-octynoic acid (Dhoya)-containing cyclic depsipeptides, were isolated from a shallow subtidal collection of a “button” cyanobacterium (Rivularia sp.) from near the island of Vieques, Puerto Rico ...
Paul D. Boudreau (776846)   +4 more
core   +1 more source

The Investigation of “Impossible” Ring Sizes in the Macrocyclooligomerization of Depsipeptides and The Development and Mechanistic Exploration of RyR2 Selective Inhibitors

open access: yes, 2022
Cyclooligomeric depsipeptides display a diverse range of biological activity and hold strong promise as potential therapeutics. However, the development of drug molecules in this larger size regime is still far less explored than traditional small ...
Smith, Abigail Nicole
core  

Saroclides A and B, Cyclic Depsipeptides from the Mangrove-Derived Fungus Sarocladium kiliense HDN11-112

open access: yes, 2018
Two new depsipeptides (1 and 2), together with three known related compounds, pestalotin (3), pestalotiopyrone L (4), and PC-2 (5), were discovered in the extract of a mangrove derived fungus Sarocladium kiliense HDN11-112. The structures of saroclides A
Na Li (6550)   +7 more
core   +1 more source

Biologically active cyclic depsipeptides from marine cyanobacteria

open access: yes
This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites.
Medina, Rebecca A.
core  

Rakicidin J and K, two cytotoxic and antibacterial cyclic depsipeptides from the marine bacterium Micromonospora chalcea

open access: yes
Rakicidin J (1) and rakicidin K (2), two new cyclic depsipeptides, were isolated from culture broth of Micromonospora chalcea FIM-R150103. Their structures were elucidated by extensive analysis of NMR, HR-ESI-MS, and electronic circular dichroism (ECD ...
Li Chen (5749)   +9 more
core   +1 more source

Human skin kinetics of cyclic depsipeptide mycotoxins

open access: yes, 2014
Cyclic depsipeptides (CDPs) are an emerging group of naturally occurring bioactive peptides, some of which are already developed as pharmaceutical drugs, e.g. valinomycin. They are produced by bacteria, marine organisms and fungi [1]. Some CDPs are secondary fungal metabolites, which can be very toxic to humans and animals, and are therefore called ...
Taevernier, Lien   +3 more
openaire   +1 more source

Skin, mucosal and blood-brain barrier kinetics of model cyclic depsipeptides : the mycotoxins beauvericin and enniatins

open access: yes, 2016
This research takes off by giving an introduction to the wonderful world of the chemically very diverse cyclic depsipeptides (CDPs). This family of compounds is biosynthetically produced by an extreme variety of natural organisms, such as bacteria and ...
Taevernier, Lien
core  

Cyclické peptidy a depsipeptidy jako markery houbových infekcí

open access: yes, 2004
Fungi produce cyclic peptides and depsipeptides by multifunctional ...
Jegorov, A.
core  

Home - About - Disclaimer - Privacy