Results 91 to 100 of about 497 (160)

Total Synthesis of the Cyclic Depsipeptide YM-280193, a Platelet Aggregation Inhibitor

Organic Letters, 2015
The first total synthesis of YM-280193, a cyclic depsipeptide that inhibits the ADP-induced aggregation of human platelets, is described. The monomer and dipeptide fragments were prepared using conventional chemistry and subsequently assembled by Fmoc-solid-phase peptide synthesis (Fmoc-SPPS).
Kaur, Harveen, Harris, Paul W. R., Little, Peter J., Brimblet, Margaret A.   +3 more
openaire   +5 more sources

Ionophoric Activity of Cyclic Depsipeptides from Beauveria bassiana

, 2022
Beauvericin and bassianolide are cyclodepsipeptides produced as secondary metabolites by the fungus Beauveria bassiana. Depsipeptides are molecules of high interest, since some of them show high potential for pharmaceutical applications.
Theuerkauf, Marie
core  

Isolation and Structures of Pipecolidepsins A and B, Cytotoxic Cyclic Depsipeptides from the Madagascan Sponge Homophymia lamellosa

, 2016
Two new cyclic depsipeptides, pipecolidepsins A and B (1 and 2), have been isolated from the sponge Homophymia lamellosa collected off the coast of Madagascar.
Rogelio Fernández (1812538), Carmen Cuevas (223465), María Jesús Martín (1812520), Laura Coello (1840399), Fernando Reyes (444361)   +4 more
core   +1 more source

Elucidation of novel turnagainolides and their biosynthetic gene cluster in Bacillus subtilis

Applied and Environmental Microbiology
Turnagainolides represent a unique class of cyclic depsipeptides characterized by the presence of a rare (E)-3-hydroxy-5-phenylpent-4-enoic acid (Hppa) residue, exhibiting diverse bioactivities.
Peng Li, Shuang Han, Min Wang, Xuejiao Zhang, Shuai Zhi, Meiling Jin, Jouni Jokela, Shan He, Liwei Liu   +8 more
doaj   +1 more source

Stereoselective Strategies for the Construction of Cyclic Peptides, Depsipeptides, Sugars, and Alkenes [PDF]

, 2017
Cyclic peptides have attracted attention due to their promising metabolic stability, conformational rigidity, and potential to mimic protein−protein interactions.
Le, Diane Nguyen
core  

Synthesis of conformationally restricted cyclic pentadepsipeptides via direct amide cyclization

, 2001
The 2,2-disubstituted 2H-azirin-3-amines 6 (3-amino-2H-azirines) were used as building blocks for alpha,alpha-disubstituted alpha-amino acids in the preparation of 16-membered cyclic depsipeptides 14.
Koch, Kristian N, Heimgartner, Heinz, Linden, Anthony; https://orcid.org/   +2 more
core   +1 more source

Marine Tunicate, the Electuary of Mithridates

Iranian South Medical Journal, 2015
Tunicates are a large group of marine animals and have been named “tunicate” because of cellosic outer covering called a tunic. They are divided into four major classes of the ascidians, thaliaceans, appendicularians and Sorberacea. Ascidians
Gholam hosean Mohebbi, Saeadh samira Arshadi, Iraj Nabipour, Khalil Pourkhalili   +3 more
doaj  

Total Synthesis of the Cyclic Depsipeptide Leualacin [PDF]

The Journal of Organic Chemistry, 1995
openaire   +2 more sources

Mirabamides A–D, Depsipeptides from the Sponge Siliquariaspongia mirabilis That Inhibit HIV-1 Fusion

, 2016
Four new cyclic depsipeptides termed mirabamides A–D (1–4) have been isolated from the marine sponge Siliquariaspongia mirabilis and shown to potently inhibit HIV-1 fusion.
Elena Gustchina (237584), Carole A. Bewley (237605), Michelle Kelly (109768), Alberto Plaza (1541617), Heather L. Baker (1307841)   +4 more
core   +1 more source

Aminoacid sequencing in cyclic peptides and depsipetides

, 2001
Natural or synthetic cyclic peptides and depsipeptides involve antibiotics, toxins, immunomodulators, ion transport regulators, and inhibitors of enzymes or protein-protein ...
Havlíček, Vladimír
core