Results 221 to 230 of about 14,640,780 (243)

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

STING agonist profiling by nucleotide library defines structural determinants of cyclic dinucleotide recognition. [PDF]

iScience
Bekere I, Hubarzhevska Y, Egender SV, Quoika PK, Öllinger R, Schrimpf MR, Rad R, Zacharias M, de Oliveira Mann CC.   +8 more
europepmc   +1 more source

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Contribution of Cyclic and Pseudo-cyclic Electron Transport to the Formation of Proton Motive Force in Chloroplasts

Molecular Plant, 2017
Hiroshi Yamamoto, Tohsiharu Shikanai
exaly  

Cyclic spectral analysis in practice

Mechanical Systems and Signal Processing, 2007
Jérôme Antoni
exaly  

Guanosine 3':5'-Cyclic Monophosphate: A Possible Intracellular Mediator of Mitogenic Influences in Lymphocytes

Proceedings of the National Academy of Sciences of the United States of America, 1972
M K Haddox, John W Hadden, E M Hadden
exaly  

The Importance of Calcium Ions for the Regulation of Guanosine 3':5'-Cyclic Monophosphate Levels

Proceedings of the National Academy of Sciences of the United States of America, 1973
E W Sutherland, Joel G Hardman
exaly  

Benchmark experiments and characteristic cyclic plasticity deformation

International Journal of Plasticity, 2008
Yanyao Jiang, Jixi Zhang
exaly  

Direct conversion of CO2 with diols, aminoalcohols and diamines to cyclic carbonates, cyclic carbamates and cyclic ureas using heterogeneous catalysts

Journal of Chemical Technology and Biotechnology, 2014
Yoshinao Nakagawa, Masazumi Tamura, Masayoshi Honda   +2 more
exaly  

Complexity of cyclic scheduling problems: A state-of-the-art survey

Computers and Industrial Engineering, 2010
David Alcaide López de Pablo, Eugene Levner, Vladimir Kats   +2 more
exaly