Results 1 to 10 of about 530 (149)
Heliyon, 2023 Cyclic-di-AMP (c-di-AMP) is an important secondary messenger molecule that plays a critical role in monitoring several important cellular processes, especially in several Gram-positive bacteria.
Vikas Chaudhary +3 more
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Two-step synthesis and hydrolysis of cyclic di-AMP in Mycobacterium tuberculosis. [PDF]
PLoS ONE, 2014 Cyclic di-AMP is a recently discovered signaling molecule which regulates various aspects of bacterial physiology and virulence. Here we report the characterization of c-di-AMP synthesizing and hydrolyzing proteins from Mycobacterium tuberculosis ...
Kasi Manikandan +5 more
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Acta Biochimica et Biophysica Sinica, 2023 Cyclic di-adenosine monophosphate (c-di-AMP) is a bacterial second messenger that can be recognized by infected host cells and activate the immunoinflammatory response.
Chen Sirui +8 more
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The World of Cyclic Dinucleotides in Bacterial Behavior
Molecules, 2020 The regulation of multiple bacterial phenotypes was found to depend on different cyclic dinucleotides (CDNs) that constitute intracellular signaling second messenger systems.
Aline Dias da Purificação +4 more
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(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in
mBio, 2020 The facultative intracellular pathogen Listeria monocytogenes, like many related Firmicutes, uses the nucleotide second messenger cyclic di-AMP (c-di-AMP) to adapt to changes in nutrient availability, osmotic stress, and the presence of cell wall-acting ...
Bret N. Peterson +8 more
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Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant. [PDF]
PLoS Genetics, 2018 The broadly conserved bacterial signalling molecule cyclic-di-adenosine monophosphate (c-di-AMP) controls osmoresistance via its regulation of potassium (K+) and compatible solute uptake.
Huong Thi Pham +13 more
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npj Biofilms and Microbiomes, 2022 Microbial pathogens employ signaling systems through cyclic (di-) nucleotide monophosphates serving as second messengers to increase fitness during pathogenesis.
M. Fata Moradali +5 more
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Cyclic Dinucleotides in Oral Bacteria and in Oral Biofilms
Frontiers in Cellular and Infection Microbiology, 2017 Oral cavity acts as a reservoir of bacterial pathogens for systemic infections and several oral microorganisms have been linked to systemic diseases.
Ulvi K. Gürsoy +4 more
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The role of bacterial cyclic di-adenosine monophosphate in the host immune response
Frontiers in Microbiology, 2022 Cyclic di-adenosine monophosphate (c-di-AMP) is a second messenger which is widely used in signal transduction in bacteria and archaea. c-di-AMP plays an important role in the regulation of bacterial physiological activities, such as the cell cycle, cell
Xingqun Cheng +3 more
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Immunization with Tc52 or its amino terminal domain adjuvanted with c-di-AMP induces Th17+Th1 specific immune responses and confers protection against Trypanosoma cruzi. [PDF]
PLoS Neglected Tropical Diseases, 2017 The development of new adjuvants enables fine modulation of the elicited immune responses. Ideally, the use of one or more adjuvants should result in the induction of a protective immune response against the specific pathogen.
Marina N Matos +5 more
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