Results 11 to 20 of about 31,021,495 (194)

Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]

, 2013
Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
core   +1 more source

Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus. [PDF]

PLoS Genetics, 2018
Cyclic nucleotides are universally used as secondary messengers to control cellular physiology. Among these signalling molecules, cyclic di-adenosine monophosphate (c-di-AMP) is a specific bacterial second messenger recognized by host cells during ...
Laura Devaux, Dona Sleiman, Maria-Vittoria Mazzuoli, Myriam Gominet, Philippe Lanotte, Patrick Trieu-Cuot, Pierre-Alexandre Kaminski, Arnaud Firon   +7 more
doaj   +1 more source

Homeostasis of Second Messenger Cyclic-di-AMP Is Critical for Cyanobacterial Fitness and Acclimation to Abiotic Stress

Frontiers in Microbiology, 2018
Second messengers are intracellular molecules regulated by external stimuli known as first messengers that are used for rapid organismal responses to dynamic environmental changes.
Marco Agostoni, Marco Agostoni, Alshaé R. Logan-Jackson, Alshaé R. Logan-Jackson, Emily R. Heinz, Geoffrey B. Severin, Eric L. Bruger, Christopher M. Waters, Christopher M. Waters, Beronda L. Montgomery, Beronda L. Montgomery, Beronda L. Montgomery, Beronda L. Montgomery   +12 more
doaj   +1 more source

c-di-AMP Accumulation Regulates Growth, Metabolism, and Immunogenicity of Mycobacterium smegmatis

Frontiers in Microbiology, 2022
Cyclic dimeric adenosine monophosphate (c-di-AMP) is a ubiquitous second messenger of bacteria involved in diverse physiological processes as well as host immune responses.
Huanhuan Ning, Xuan Liang, Xuan Liang, Yanling Xie, Yanling Xie, Lu Bai, Lu Bai, Wei Zhang, Lifei Wang, Jian Kang, Yanzhi Lu, Yanling Ma, Guangchun Bai, Yinlan Bai   +13 more
doaj   +1 more source

c-di-AMP signaling plays important role in determining antibiotic tolerance phenotypes of Mycobacterium smegmatis

Scientific Reports, 2022
In this study, we probe the role of secondary messenger c-di-AMP in drug tolerance, which includes both persister and resistant mutant characterization of Mycobacterium smegmatis.
Aditya Kumar Pal, Anirban Ghosh
doaj   +1 more source

Subunit Vaccine ESAT-6:c-di-AMP Delivered by Intranasal Route Elicits Immune Responses and Protects Against Mycobacterium tuberculosis Infection

Frontiers in Cellular and Infection Microbiology, 2021
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, remains the most common cause of death from a single infectious disease. More safe and effective vaccines are necessary for preventing the prevalence of TB. In this study, a subunit
Huanhuan Ning, Huanhuan Ning, Wei Zhang, Jian Kang, Tianbing Ding, Xuan Liang, Yanzhi Lu, Chengxuan Guo, Wenjie Sun, Huapeng Wang, Yinlan Bai, Lixin Shen   +11 more
doaj   +1 more source

Sustained Control of Pyruvate Carboxylase by the Essential Second Messenger Cyclic di-AMP in Bacillus subtilis

mBio, 2022
In Bacillus subtilis and other Gram-positive bacteria, cyclic di-AMP is an essential second messenger that signals potassium availability by binding to a variety of proteins.
Larissa Krüger, Christina Herzberg, Dennis Wicke, Patricia Scholz, Kerstin Schmitt, Asan Turdiev, Vincent T. Lee, Till Ischebeck, Jörg Stülke   +8 more
doaj   +1 more source

C-di-AMP Is a Second Messenger in Corynebacterium glutamicum That Regulates Expression of a Cell Wall-Related Peptidase via a Riboswitch

Microorganisms, 2023
Cyclic di-adenosine monophosphate (c-di-AMP) is a bacterial second messenger discovered in Bacillus subtilis and involved in potassium homeostasis, cell wall maintenance and/or DNA stress response.
Sebastian J. Reich, Oliver Goldbeck, Tsenguunmaa Lkhaasuren, Dominik Weixler, Tamara Weiß, Bernhard J. Eikmanns   +5 more
doaj   +1 more source

Cyclic Di-adenosine Monophosphate Regulates Metabolism and Growth in the Oral Commensal Streptococcus mitis

Microorganisms, 2020
Cyclic di-adenosine monophosphate (c-di-AMP) has emerged as an important bacterial signaling molecule that functions both as an intracellular second messenger in bacterial cells and an extracellular ligand involved in bacteria-host cross-talk.
Gro Herredsvela Rørvik, Krystyna Anna Liskiewicz, Fedor Kryuchkov, Ali-Oddin Naemi, Hans-Christian Aasheim, Fernanda C. Petersen, Thomas M. Küntziger, Roger Simm   +7 more
doaj   +1 more source

The mucosal adjuvant cyclic di-AMP exerts immune stimulatory effects on dendritic cells and macrophages. [PDF]

PLoS ONE, 2014
The cyclic di-nucleotide bis-(3',5')-cyclic dimeric adenosine monophosphate (c-di-AMP) is a candidate mucosal adjuvant with proven efficacy in preclinical models.
Ivana Škrnjug, Christine Rueckert, Rimma Libanova, Stefan Lienenklaus, Siegfried Weiss, Carlos A Guzmán   +5 more
doaj   +1 more source