Results 151 to 160 of about 10,177 (227)
Bacterial β-peptidyl aminopeptidases: on the hydrolytic degradation of β-peptides [PDF]
The special chemical and biological features of β-peptides have been investigated intensively during recent years. Many studies emphasize the restricted biodegradability and the high metabolic stability of this class of compounds.
Geueke, B., Kohler, H.-P
core
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Publications of the exobiology program for 1983: A special bibliography [PDF]
A list of 1983 publications resulting from research pursued under the auspices of NASA's Exobiology Program is given. Topics in the fields of biological, chemical, and planetary evolution; geochemistry; and intelligent extraterrestrial life are ...
Devincenzi, D. L., Pleasant, L. G.
core +1 more source
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov +16 more
wiley +1 more source
The tripeptide Pro‐Pro‐D‐hVal‐OMe, which lacks an acidic group, catalysed the conjugate addition of aldehydes to nitroolefins and afforded γ‐nitroaldehydes in 79–97% yield and 88:14–93:7 e.r. The proposed reaction mechanism relies on the active role of hydrazide NHβ or NHα protons in hydrogen bonding with the reacting species.
Ivona Banović +2 more
wiley +1 more source
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti +5 more
wiley +1 more source
A new strategy for temporal control over simple and complex coacervates is described here. The urea‐urease reaction results in the timed formation and/or destruction of complex coacervates after controllable delays. This strategy is easily adaptable to different time scales and polyelectrolyte pairs.
Shana Shirin Valapra +4 more
wiley +1 more source
Amino acid chlorides: A journey from instability and racemization toward broader utility in organic synthesis including peptides and their mimetics Dedicated to Professor Padmanabhan Balaram, Indian Institute of Science, Bangalore on the occasion of his superannuation [PDF]
Basavaprabhu, . +4 more
core +1 more source
Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat +16 more
wiley +1 more source
The crystal structures of Arabidopsis thaliana γ‐glutamyl peptidase 1 (GGP1), including the covalent intermediate state, were determined. GGP1 is involved in both glutathione degradation in the primary metabolism and glutathione conjugate processing in the secondary metabolism of glucosinolate and camalexin biosynthesis.
Kosei Sone +7 more
wiley +1 more source

