Background Cyclic dipeptides are an important class of natural products owing to their structural diversity and biological activities. In fungi, the cyclo-ring system is formed through the condensation of two α-amino acids via non-ribosomal peptide ...
Jianzhao Qi +9 more
doaj +1 more source
We previously determined that the cyclase inhibitor tripropylamine (TPA) significantly enhances lycopene accumulation in Blakeslea trispora. To elucidate the mechanism of TPA-enhanced lycopene accumulation, the untargeted metabolome of B.
Yanlong Wang +8 more
doaj +1 more source
Fragmentation of 2,5-diketopiperazine cyclic dipeptide ions
The mechanism of radiation damage to 2,5-diketopiperazine (DKP, C4H6N2O2) molecules in the gas phase upon interaction with He2+ ions with an energy Ep = 4 keV/u has been investigated. The relative cross sections of various elementary processes occurring in single collisions of DKP with ions have been measured for the first time.
A. A. Basalaev +4 more
openaire +1 more source
Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides
The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs.
Gzona Bajraktari-Sylejmani +5 more
doaj +1 more source
Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]
In this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj +1 more source
Enzymatical and microbial degradation of cyclic dipeptides (diketopiperazines). [PDF]
Diketopiperazines (DKPs) are cyclic dipeptides, representing an abundant class of biologically active natural compounds. Despite their widespread occurrence in nature, little is known about their degradation. In this study, the enzymatical and microbial cleavage of DKPs was investigated.
Perzborn M, Syldatk C, Rudat J.
europepmc +6 more sources
Antibacterial activity of cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr) from Streptomyces sp. strain 22-4 against phytopathogenic bacteria [PDF]
Two bioactive cyclic dipeptides, cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr), were isolated from the culture broth of Streptomyces sp. strain 22-4 and tested against three economically important plant pathogens, Xanthomonas axonopodis pv.
Apichaisataienchote, Busaya +4 more
core +3 more sources
Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry [PDF]
Dynamic combinatorial chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other.
Li, Jianwei, +2 more
core +5 more sources
Advances in research on chemical constituents and pharmacological effects of Paecilomyces hepiali
Paecilomyces hepiali is a fungus with edible and pharmaceutic value, isolated from Ophiocordyceps sinensis. Its main bioactive constituents contain alkaloids, cyclic dipeptides, steroids, organic acids, and polysaccharides.
Akang Dan +5 more
doaj +1 more source
Champacyclin, a New Cyclic Octapeptide from Streptomyces Strain C42 Isolated from the Baltic Sea [PDF]
New isolates of Streptomyces champavatii were isolated from marine sediments of the Gotland Deep (Baltic Sea), from the Urania Basin (Eastern Mediterranean), and from the Kiel Bight (Baltic Sea).
Baumann, Heike Irmgard +6 more
core +2 more sources

