Results 181 to 190 of about 72,449 (334)

ACTIONS OF PAPAVERINE ON INTESTINAL SMOOTH MUSCLE AND ITS INHIBITION OF CYCLIC AMP AND CYCLIC GMP PHOSPHODIESTERASES

, 1976
Masaaki Miyamoto, Issei Takayanagi, Hideo Ohkubo, Keijiro Takagi   +3 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

A Bioengineered In Vitro Model to Assess AAV-Based Gene Therapies for Cyclic GMP-Related Disorders. [PDF]

Int J Mol Sci, 2022
Pavlou M, Babutzka S, Michalakis S.
europepmc   +1 more source

Depressed cardiac cyclic GMP-dependent protein kinase in spontaneously hypertensive rats and its further depression by guanethidine

, 1976
J.F. Kuo, Craig W. Davis, James Tse
openalex   +1 more source

Inhibition of chemotaxis Ng-monomethyl-L-arginine: a role for cyclic GMP [PDF]

, 1989
SS Kaplan, Timothy R. Billiar, RD Curran, UE Zdziarski, R L Simmons, RE Basford   +5 more
openalex   +1 more source

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

ELECTROPHORESIS, EarlyView.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht, Cari E. Sänger ‐ van de Griend   +1 more
wiley   +1 more source

BdGUCD1 and Cyclic GMP Are Required for Responses of Brachypodium distachyon to Fusarium pseudograminearum in the Mechanism Involving Jasmonate. [PDF]

Int J Mol Sci, 2022
Duszyn M, Świeżawska-Boniecka B, Skorupa M, Jaworski K, Szmidt-Jaworska A.   +4 more
europepmc   +1 more source

Localization of cyclic GMP-dependent protein kinase and substrate in mammalian cerebellum. [PDF]

, 1980
D Schlichter, John A. Detre, Dana W. Aswad, Bahram Chehrazi, Paul Greengard   +4 more
openalex   +1 more source

Personalized Cancer Immunotherapy Boosted by cGAS‐STING‐Targeted Nanovaccines in Combination With Nutrient Modulation

Exploration, EarlyView.
The engineered bacteria (2'3'‐cGAMP@E.coli) is designed to synthesize intracellular 2'3'‐cGAMP, enabling the assembly of personalized nanovaccines (nECTs) through a bioconjugation with autologous tumor antigens, circumventing elaborate chemical production processes. The therapeutic impact of nECTs is significantly amplified when combined with a fasting‐
Wenping Huang, Guoliang Cao, Mixiao Tan, Fuhao Jia, Jie Zhang, Wen Su, Yue Yin, Hai Wang   +7 more
wiley   +1 more source

An off-target effect of class A CpG-oligonucleotides on suppressing the cyclic GMP-AMP synthase signaling in fibroblastic reticular cells. [PDF]

Front Pharmacol
Jayakumar P, Jiang T, Huang H, Deng M.
europepmc   +1 more source