Results 201 to 210 of about 450,778 (258)
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Nature, 1973
THE movement of mammalian cells can be inhibited by agents which mimic or produce increases in the intracellular levels of cyclic 3′,5′-adenosine monophosphate (cyclic AMP)1,2. Goldberg and coworkers3,4 have proposed that in a number of cell types cyclic 3′,5′-guanosine monophosphate (cyclic GMP) promotes cellular events that are antagonistic to those ...
R D, Estensen +4 more
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THE movement of mammalian cells can be inhibited by agents which mimic or produce increases in the intracellular levels of cyclic 3′,5′-adenosine monophosphate (cyclic AMP)1,2. Goldberg and coworkers3,4 have proposed that in a number of cell types cyclic 3′,5′-guanosine monophosphate (cyclic GMP) promotes cellular events that are antagonistic to those ...
R D, Estensen +4 more
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Cyclic GMP signaling in podocytes
Microscopy Research and Technique, 2002AbstractNatriuretic peptides (NP), together with nitric oxide (NO) are powerful relaxing factors acting via a common second messenger, cyclic GMP (cGMP). Together with other vasoactive modulators, these vasorelaxing factors play an essential role in regulating the function of kidney glomeruli.
Barbara, Lewko, Jan, Stepinski
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Clinical Relationships of Cyclic GMP
1994Publisher Summary The purpose of this chapter is to review current knowledge on the clinical use of cyclic guanosine monophosphate (cGMP) measurements as markers of endogenous and exogenous ANP effects. cGMP production through the stimulation of particulate guanylate cyclase is induced by the action of atrial natriuretic peptide (ANP) on target cells.
J R, Cusson +5 more
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Annual Review of Pharmacology, 1974
A chapter on "Cyclic AMP and Drug Action" has already been published in Annual Review of Pharmacology (1). In spite of its restrictive title, this paper covered most of the knowledge about the biochemical and biological effects of cAMP that was available in 1969.
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A chapter on "Cyclic AMP and Drug Action" has already been published in Annual Review of Pharmacology (1). In spite of its restrictive title, this paper covered most of the knowledge about the biochemical and biological effects of cAMP that was available in 1969.
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Cyclic GMP-Hydrolyzing Phosphodiesterases
2009The cyclic nucleotides (cN), cAMP and cGMP, are key second messengers that mediate the intracellular effects of many signals known as “first messengers”, including environmental signals such as photons for vision and chemicals for taste, as well as hormones, paracrine factors, neurotransmitters, or autocrine factors.
Sharron H, Francis +2 more
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Cyclic GMP and mechanisms of vasodilation
Pharmacology & Therapeutics, 1989This review is the result of a widening interest in the role of cGMP in vascular smooth muscle function. Smooth muscle physiologists, pharmacologists, and biochemists now appreciate the fact that cGMP plays a key role in regulating vascular, and probably non-vascular, smooth muscle contractile ...
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The measurement of cyclic GMP and cyclic AMP phosphodiesterases
Analytical Biochemistry, 1979Abstract Methods are described for measuring phosphodiesterases for cGMP and cAMP in the range of activity yielding 10 −12 to 10 −8 mol of product. The 5′-GMP formed is measured by conversion to GDP with guanylate kinase. Amounts of GDP greater than 10 −10 mol are measured directly with an enzyme system which results in stoichiometric oxidation of
J G, Carter, S J, Berger, O H, Lowry
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The role of cyclic AMP and cyclic GMP in byssinosis
American Industrial Hygiene Association Journal, 1979The lungs of female guinea pigs, either untreated or previously sensitized with aqueous extracts of cotton dust (AECD) were perfused via the pulmonary artery with 0, 10-6, 10-5 or 10-4 g/mL of lyophilized AECD in Tyrodes solution. Pressure changes in the pulmonary artery were monitored during this period.
M H, Elissalde, G A, Greenblatt
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1994
Publisher Summary This chapter focuses on the lower forms of life—that is, single-celled organisms. It briefly reviews the literature on cyclic guanosine monophosphate (cGMP) in bacteria and then describes two systems that have been studied frequently—the slime mold ( Dictyostelium discoideum ) and the protozoans ( Paramecium and Tetrahymena ). The
J E, Schultz, S, Klumpp
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Publisher Summary This chapter focuses on the lower forms of life—that is, single-celled organisms. It briefly reviews the literature on cyclic guanosine monophosphate (cGMP) in bacteria and then describes two systems that have been studied frequently—the slime mold ( Dictyostelium discoideum ) and the protozoans ( Paramecium and Tetrahymena ). The
J E, Schultz, S, Klumpp
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Cyclic GMP System in the Epidermis
2015A great deal of knowledge has been gained concerning the activation of adenylate and guanylate cyclase in epidermal cells. Adenylate cyclase is activated by 4 different independent receptors-responding respectively to catecholamine (beta), to prostaglandins (E), to histamine (H2), and to adenosine and it phosphorylated derivatives.
K, Adachi +4 more
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