Results 201 to 210 of about 611,110 (302)

Inhibitors of the Cyclic GMP-AMP Synthase (cGAS) as Potential Treatment for Autoimmune and Inflammatory Diseases. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source

Beyond Initial Adoption: How Lean Six Sigma Is Sustained, Adapted, and Used in the U.S. Textile and Apparel Industry

Quality and Reliability Engineering International, EarlyView.
ABSTRACT This study examines how Lean Six Sigma (LSS) currently functions in the U.S. textile and apparel industry after years of adoption and use. Moving beyond isolated project‐level evidence, this study investigates whether LSS has been implemented as an organizational capability and integrated into the corporate culture, adapted to textile‐specific
Alireza Vahedi Fakhr, A. Blanton Godfrey, Warren J. Jasper   +2 more
wiley   +1 more source

Regulation and Pharmacology of the Cyclic GMP and Nitric Oxide Pathway in Embryonic and Adult Stem Cells. [PDF]

Cells
Kots AY, Bian K.
europepmc   +1 more source

Engineering Flexible Nanofibrous Hydroxyapatite Scaffolds With Tunable Degradation and Mechanical Properties for Bone Regeneration

Small, EarlyView.
Conventional hydroxyapatite ceramics are brittle and poorly resorbable, limiting their use in bone repair. To overcome these limitations, flexible scaffolds are fabricated using ceramic nanofibers as structural building blocks. Adjusting nanofiber characteristics allows modulating the mechanical properties and degradation, providing a versatile ...
Raúl Agut López, Ignacio Ridao Laguna, Cristián Huck‐Iriart, Maria‐Pau Ginebra, Montserrat Espanol   +4 more
wiley   +1 more source

Multi‐State Resistance in Microtubule‐Templated Gold Nanowires

Small, EarlyView.
The scaling limits of CMOS transistors require alternative, dynamically reconfigurable nanoscale devices. This study demonstrates the multi‐state resistance in pure gold nanowires templated by microtubules. Continuous nanowires with local inhomogeneities enable electromigration‐driven, multistate resistance modulation under voltage pulses, while ...
Borja Rodriguez‐Barea, Brenda Palestina Romero, Charlotte Kielar, René Hübner, Stefan Diez, Artur Erbe   +5 more
wiley   +1 more source

Biomaterial Platforms for Spatiotemporal Control of mRNA Delivery in Tissue Engineering and Regenerative Medicine: Design Rules, Therapeutic Applications, and Translational Roadmap

Small, EarlyView.
Biomaterial platforms can control where and when mRNA‐encoded proteins are expressed to support tissue repair. This Review proposes a cargo–target–timing framework linking therapeutic function, target tissues and cells, and expression profiles with carrier and scaffold design.
Huachun Pan, Shumin Yang, Katarina Holubova, Huifang Yin, Hongbo Chen, Xintian Zheng, Xiangan Han, Jinqiu Zhang, Xueping Li, Hui Zhang, Xiaojun Cai, Václav Slovák, Lihong Zhang, Quan Mo, Quazi T. H. Shubhra   +14 more
wiley   +1 more source

Regulation of calcium entry by cyclic GMP signaling in Toxoplasma gondii. [PDF]

J Biol Chem
Hortua Triana MA, Márquez-Nogueras KM, Fazli MS, Quinn S, Moreno SNJ.   +4 more
europepmc   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

Smart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag, Subhasis Banerjee, Sabyasachi Banerjee, Sourav De, S. K. Ashok Kumar, Yan‐Jye Shyong, Subhankar Mukhopadhyay   +6 more
wiley   +1 more source

The regulatory mechanism of cyclic GMP-AMP synthase on inflammatory senescence of nucleus pulposus cell. [PDF]

J Orthop Surg Res
Sun R, Wang F, Zhong C, Shi H, Peng X, Gao JW, Wu XT.   +6 more
europepmc   +1 more source

Understanding the Dynamics of Mechanically Interlocked Molecular Systems via Metadynamics Simulations

The Chemical Record, EarlyView.
This Personal Account discusses how molecular simulations help uncover motion, shuttling mechanisms, and kinetics in mechanically interlocked molecules such as rotaxanes and catenanes. Mechanically interlocked molecules, such as rotaxanes and catenanes, display complex internal dynamics and reciprocal motions that are central to their use as artificial
Clara Sabrià, Luigi Leanza, Massimo Delle Piane, Max von Delius, Ferran Feixas, Xavi Ribas, Giovanni M. Pavan   +6 more
wiley   +1 more source