Results 11 to 20 of about 433,779 (173)

Treatment of staphylococcal infections with cyclic lipopeptides [PDF]

open access: yesClinical Microbiology and Infection, 2008
Daptomycin is the first of a new class of antibiotics, the cyclic lipopeptides, for which a novel mechanism of action is hypothesised. Owing to its mode of action, daptomycin is rapidly bactericidal without being bacteriolytic, is active against static- and growing-phase bacteria, and has a low resistance rate in vitro.
B.I. Eisenstein, Eisenstein, B.I.
openaire   +4 more sources

Bacterial Aggregation Assay in the Presence of Cyclic Lipopeptides

open access: yesBio-Protocol, 2018
Lipopeptides is an important class of biosurfactants having antimicrobial and anti-adhesive activity against pathogenic bacteria. These include surfactin, fengycin, iturin, bacillomycin, mycosubtilin, lichenysin, and pumilacidin (Arima et al., 1968 ...
Pengyuan Xiu   +3 more
doaj   +4 more sources

The antimicrobial compound xantholysin defines a new group of Pseudomonas cyclic lipopeptides. [PDF]

open access: yesPLoS ONE, 2013
The rhizosphere isolate Pseudomonas putida BW11M1 produces a mixture of cyclic lipopeptide congeners, designated xantholysins. Properties of the major compound xantholysin A, shared with several other Pseudomonas lipopeptides, include antifungal activity
Wen Li   +9 more
doaj   +3 more sources

Evaluation of effect the cyclic lipopeptides from Bacillus atrophaeus HNSQJYH170 on Candida species

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: In humans, during the recent years, several factors have increased the risk of fungal infections, like broad spectrum antibiotics, immune compromised patients, cytotoxic chemotherapy and transplantations.
Solmaz Moghtadi pisheh, Mahboobeh madani
doaj   +1 more source

New multicomponent strategies to cyclic lipopeptides [PDF]

open access: yes, 2018
Peptide functionalization and macrocyclization stands among the most challenging issues in peptide chemistry. While derivatization endows the peptide scaffold with some desired features, such as, reactive or biologically active moieties, cyclization is commonly used to anchor bioactive conformations as well as to study the structure-activity ...
Chávez Morejón, Micjel
openaire   +3 more sources

Lipopeptides as rhizosphere public goods for microbial cooperation [PDF]

open access: yesMicrobiology Spectrum, 2023
Cyclic lipopeptides (CLPs) are key bioactive secondary metabolites produced by some plant beneficial rhizobacteria such as Pseudomonas and Bacillus. They exhibit antimicrobial properties, promote induced systemic resistance in plants, and support key ...
Augustin Rigolet   +7 more
doaj   +2 more sources

Solid-Phase Synthesis of Biaryl Cyclic Lipopeptides Derived from Arylomycins

open access: yesACS Omega, 2020
An efficient approach for the solid-phase synthesis of N-methylated tailed biaryl cyclic lipopeptides based on the structure of arylomycins was established. Each of these analogues incorporates an N-terminal linear lipopeptide attached to a biaryl cyclic
Iteng Ng-Choi   +4 more
doaj   +2 more sources

Chemical diversity and cellular effects of antifungal cyclic lipopeptides from cyanobacteria [PDF]

open access: yes, 2021
Cyanobacteria produce a variety of chemically diverse cyclic lipopeptides with potent antifungal activities. These cyclic lipopeptides have an amphipathic structure comprised of a polar peptide cycle and hydrophobic fatty acid side chain.
Fewer, David P.   +15 more
core   +1 more source

Semi-synthetic puwainaphycin/minutissamide cyclic lipopeptides with improved antifungal activity and limited cytotoxicity [PDF]

open access: yes, 2021
Microbial cyclic lipopeptides are an important class of antifungal compounds with applications in pharmacology and biotechnology. However, the cytotoxicity of many cyclic lipopeptides limits their potential as antifungal drugs.
Saurav, Kumar   +14 more
core   +1 more source

Iturin: A Promising Cyclic Lipopeptide with Diverse Applications

open access: yesBiomolecules, 2023
This comprehensive review examines iturin, a cyclic lipopeptide originating from Bacillus subtilis and related bacteria. These compounds are structurally diverse and possess potent inhibitory effects against plant disease-causing bacteria and fungi. Notably, Iturin A exhibits strong antifungal properties and low toxicity, making it valuable for bio ...
Deepak A. Yaraguppi   +3 more
openaire   +3 more sources

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