Results 31 to 40 of about 433,779 (173)

Genetic and functional characterization of the gene cluster directing the biosynthesis of putisolvin I and II in Pseudomonas putida strain PCL1445 [PDF]

, 2008
Pseudomonas putida PCL1445 secretes two cyclic lipopeptides, putisolvin I and putisolvin II, which possess a surface-tension-reducing ability, and are able to inhibit biofilm formation and to break down biofilms of Pseudomonas species including ...
Dubern, J.F., Stiekema, W.J., Coppoolse, E.R., Bloemberg, G.V.   +3 more
core   +1 more source

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

Iturinic Lipopeptide Diversity in the Bacillus subtilis Species Group – Important Antifungals for Plant Disease Biocontrol Applications

Frontiers in Microbiology, 2019
Iturins and closely related lipopeptides constitute a family of antifungal compounds known as iturinic lipopeptides that are produced by species in the Bacillus subtilis group.
Christopher A. Dunlap, Michael J. Bowman, Alejandro P. Rooney   +2 more
doaj   +1 more source

The Hydrophobicity and Antifungal Potentiation of Burkholdine Analogues

Molecules, 2022
The burkholdines are a family of cyclic lipopeptides reported to exhibit antifungal activity. We synthesized a series of 18 burkholdine analogues in good yield by conventional Fmoc-SPPS followed by cyclization with DIPCI/HOBt in the solution phase ...
Hiroyuki Konno, Mio Sasaki, Hinata Sano, Keima Osawa, Kazuto Nosaka, Shigekazu Yano   +5 more
doaj   +1 more source

Peptidoglycan-Associated Cyclic Lipopeptide Disrupts Viral Infectivity [PDF]

Journal of Virology, 2019
In this article, we consider a role for bacteria in shaping coronavirus infection. Taking cues from studies of enteric viruses, we initially investigated how bacterial surface components might improve CoV infection. Instead, we found that peptidoglycan-associated surfactin is a potent viricidal compound that disrupts virion integrity with broad ...
Bryan A. Johnson, Adam Hage, Birte Kalveram, Megan Mears, Jessica A. Plante, Sergio E. Rodriguez, Zhixia Ding, Xuemei Luo, Dennis Bente, Shelton S. Bradrick, Alexander N. Freiberg, Vsevolod Popov, Ricardo Rajsbaum, Shannan Rossi, William K. Russell, Vineet D. Menachery   +15 more
openaire   +3 more sources

Daptomycin: A cyclic lipopeptide antimicrobial agent

Clinical Therapeutics, 2004
The aims of this article were: to summarize the pharmacology, pharmacokinetics, and efficacy of daptomycin; to explore its safety profile; and to discuss its current and potential roles as an antimicrobial therapy.A literature search was conducted using the MEDLINE (1966-August 2004) and International Pharmaceutical Abstracts (1970-August 2004 ...
Jeu, LilyAnn, Fung, Horatio B.
openaire   +2 more sources

Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs

Frontiers in Chemistry, 2020
Herein is described the introduction of lipid moieties onto a simplified teixobactin pharmacophore using a modified Cysteine Lipidation on a Peptide or Amino acid (CLipPA) technique, whereby cysteine was substituted for 3-mercaptopropionic acid (3-MPA ...
Victor V. Yim, Victor V. Yim, Alan J. Cameron, Alan J. Cameron, Alan J. Cameron, Iman Kavianinia, Iman Kavianinia, Iman Kavianinia, Paul W. R. Harris, Paul W. R. Harris, Paul W. R. Harris, Margaret A. Brimble, Margaret A. Brimble, Margaret A. Brimble   +13 more
doaj   +1 more source

Formation and structural features of micelles formed by surfactin homologues

Frontiers in Bioengineering and Biotechnology, 2023
Surfactin, a group of cyclic lipopeptides produced by Bacillus subtilis, possesses surfactant properties and is a promising natural and biologically active compound.
Michał Bochynek, Michał Bochynek, Agnieszka Lewińska, Agnieszka Lewińska, Maciej Witwicki, Agnieszka Dębczak, Marcin Łukaszewicz, Marcin Łukaszewicz   +7 more
doaj   +1 more source

Insights into the Defense-Related Events Occurring in Plant Cells Following Perception of Surfactin-Type Lipopeptide from Bacillus subtilis

Molecular Plant-Microbe Interactions, 2009
Multiple strains of Bacillus subtilis were demonstrated to stimulate plant defense responses, and cyclic lipopeptides may be involved in the elicitation of this induced systemic resistance phenomenon.
E. Jourdan, G. Henry, F. Duby, J. Dommes, J. P. Barthélemy, P. Thonart, M. Ongena   +6 more
doaj   +1 more source

Versatile role of Pseudomonas fuscovaginae cyclic lipopeptides in plant and microbial interactions

Frontiers in Plant Science, 2022
Pseudomonas fuscovaginae is the most prominent bacterial sheath rot pathogen, causing sheath brown rot disease in rice. This disease occurs worldwide and it is characterized by typical necrotic lesions on the sheath, as well as a reduction in the number ...
Enrico Ferrarini, Mihael Špacapan, Van Bach Lam, Andrea McCann, Catherine Cesa-Luna, Bishnu Prasad Marahatta, Edwin De Pauw, René De Mot, Vittorio Venturi, Monica Höfte   +9 more
doaj   +1 more source