Results 41 to 50 of about 433,779 (173)

Inhibition of Lipopolysaccharide Activity by a Bacterial Cyclic Lipopeptide Surfactin [PDF]

The Journal of Antibiotics, 2006
Compounds that inactivate lipopolysaccharide (LPS) activity have the potential of being new anti-inflammatory agents. Therefore, we searched among microbial secondary metabolites for compounds that inhibited LPS-stimulated adhesion between human umbilical vein endothelial cells (HUVEC) and HL-60 cells.
Taichi, Takahashi, Osamu, Ohno, Yoko, Ikeda, Ryuichi, Sawa, Yoshiko, Homma, Masayuki, Igarashi, Kazuo, Umezawa   +6 more
openaire   +2 more sources

Anabaenolysins, novel cytolytic lipopeptides from benthic Anabaena cyanobacteria. [PDF]

PLoS ONE, 2012
Two novel cyclic lipopeptides, anabaenolysin A and anabaenolysin B, were isolated from two benthic cyanobacterial strains of the genus Anabaena. This novel class of cyanobacterial lipopeptides has a general structure of a small peptide ring consisting of
Jouni Jokela, Linn Oftedal, Lars Herfindal, Perttu Permi, Matti Wahlsten, Stein Ove Døskeland, Kaarina Sivonen   +6 more
doaj   +1 more source

C-Locked Analogs of the Antimicrobial Peptide BP214

Antibiotics, 2022
BP214 is an all-D antimicrobial peptide amide, kklfkkilryl, which shows an excellent activity against colistin-resistant Acinetobacter baumannii and a low hemolytic activity.
Ida Kristine Lysgaard Andersen, Thomas T. Thomsen, Jasmina Rashid, Thomas Rønnemoes Bobak, Alberto Oddo, Henrik Franzyk, Anders Løbner-Olesen, Paul R. Hansen   +7 more
doaj   +1 more source

Lipopeptides activate Gi-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells [PDF]

, 1993
Synthetic lipopeptides activate superoxide-anion (O2-) formation in human neutrophils in a pertussis-toxin (PTX)-sensitive manner, suggesting the involvement of G-proteins of the Gi family in the signal-transduction pathway.
Klinker, J. F., Schwaner, I., Wenzel-Seifert, Katharina, Seifert, Roland, Höer, A., Offermanns, S.   +5 more
core   +1 more source

A Review of the Antimicrobial Properties of Cyanobacterial Natural Products

Molecules, 2023
The development of multiple-drug-resistant pathogens has prompted medical research toward the development of new and effective antimicrobial therapies.
Ian E. Cock, Matthew J. Cheesman
doaj   +1 more source

Self-assembly of three bacterially-derived bioactive lipopeptides [PDF]

, 2013
The self-assembly in aqueous solution of three lipopeptides obtained from Bacillus subtilis has been investigated. The lipopeptides surfactin, plipastatin and mycosubtilin contain distinct cyclic peptide headgroups as well as differences in alkyl chain ...
Hamley, Ian, Ruokolainen, J., Coutte, F., Chataigne, G., Coutte, François, Chataigné, Gabrielle, Dehsorkhi, A., Jauregi, P., Jacques, P., Dehsorkhi, Ashkan, Jauregi, Paula, Seitsonen, Jani, Seitsonen, J., Hamley, I.W., Ruokolainen, Janne, Hamley, Ian W, Jacques, Philippe, Hamley, Ian W.   +17 more
core   +1 more source

Purification and characterization of antibacterial surfactin isoforms produced by Bacillus velezensis SK

AMB Express, 2022
Bacillus velezensis SK having broad-spectrum antimicrobial activity has been isolated from soil. The efficient extraction of antimicrobial compounds produced in various mediums has been done using Diaion HP-20 resin.
Sagar S. Barale, Savaliram G. Ghane, Kailas D. Sonawane   +2 more
doaj   +1 more source

Conformation and Dynamics of the Cyclic Lipopeptide Viscosinamide at the Water-Lipid Interface [PDF]

Molecules, 2019
Cyclic lipodepsipeptides or CLiPs from Pseudomonas are secondary metabolites that mediate a wide range of biological functions for their producers, and display antimicrobial and anticancer activities. Direct interaction of CLiPs with the cellular membranes is presumed to be essential in causing these.
Niels Geudens, Benjámin Kovács, Davy Sinnaeve, Feyisara Eyiwumi Oni, Monica Höfte, José C. Martins   +5 more
openaire   +4 more sources

The Discovery of Cyclic Lipopeptide Olenamidonins in a Deepsea-Derived Streptomyces Strain by Knocking Out a DtxR Family Regulator

Marine Drugs
Three new cyclic lipopeptides, olenamidonins A-C (1–3), in addition to two previously reported metabolites (4 and 5), were accumulated in the ΔdtxRso deletion mutant of deepsea-derived Streptomyces olivaceus SCSIO 1071.
Qiannan Sun, Dongqi Yu, Xueqing Zhang, Fei Xiao, Wenli Li   +4 more
doaj   +1 more source

Characterization of Cichopeptins, New Phytotoxic Cyclic Lipodepsipeptides Produced by Pseudomonas cichorii SF1-54 and Their Role in Bacterial Midrib Rot Disease of Lettuce

Molecular Plant-Microbe Interactions, 2015
The lettuce midrib rot pathogen Pseudomonas cichorii SF1-54 produces seven bioactive compounds with biosurfactant properties. Two compounds exhibited necrosis-inducing activity on chicory leaves.
Chien-Jui Huang, Ellen Pauwelyn, Marc Ongena, Delphine Debois, Valerie Leclère, Philippe Jacques, Peter Bleyaert, Monica Höfte   +7 more
doaj   +1 more source