Results 51 to 60 of about 4,338 (170)

Charting the Lipopeptidome of Nonpathogenic Pseudomonas

mSystems, 2023
A major source of pseudomonad-specialized metabolites is the nonribosomal peptide synthetases (NRPSs) assembling siderophores and lipopeptides. Cyclic lipopeptides (CLPs) of the Mycin and Peptin families are frequently associated with, but not restricted
Catherine Cesa-Luna, Niels Geudens, Léa Girard, Vic De Roo, Hassan R. Maklad, José C. Martins, Monica Höfte, René De Mot   +7 more
doaj   +1 more source

Membrane interactions of cyclic lipopeptides

, 2022
Cyclic lipopeptides (CLiPs) are amphiphilic, membrane-active, secondary metabolites produced by various organisms. They are often responsible for the plant growth-promoting and antimicrobial properties of their producers. Due to increasing resistance to pesticides and antibiotics, CLiPs have attracted more and more attention in recent years.
openaire   +2 more sources

A novel approach for the synthesis of the cyclic lipopeptide globomycin [PDF]

RSC Medicinal Chemistry
Lipid swapping: a new approach for the synthesis of globomycin that allows for facile lipid diversification.
Samantha J. Bann, Stephen A. Cochrane
openaire   +3 more sources

Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective

Advanced Science, EarlyView.
Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang, Chenhui Li, Dongjiao Wang, Qibin Wu, Zhen Zeng, Huiming Guo, Han Cheng, Songbi Chen, Hongxing Cao, Hongmei Cheng, Jianghui Xie, Youxiong Que   +11 more
wiley   +1 more source

Structure, Biosynthesis, and Biological Activity of the Cyclic Lipopeptide Anikasin

ACS Chemical Biology, 2017
The class of cyclic lipopeptide natural products consists of compounds with a diverse range of bioactivities. In this study, we elucidated the structure of the cyclic lipopeptide anikasin using X-ray crystallography, analyzed its biosynthetic gene cluster, and investigated its natural role in the interaction between the producer strain Pseudomonas ...
Sebastian Götze, Regine Herbst-Irmer, Martin Klapper, Helmar Görls, Kilian R. A. Schneider, Robert Barnett, Thomas Burks, Ursula Neu, Pierre Stallforth   +8 more
openaire   +4 more sources

Engineering of acyl ligase domain in non-ribosomal peptide synthetases to change fatty acid moieties of lipopeptides

Communications Chemistry
Cyclic lipopeptides (CLPs) produced by the genus Bacillus are amphiphiles composed of hydrophilic amino acid and hydrophobic fatty acid moieties and are biosynthesised by non-ribosomal peptide synthetases (NRPSs).
Rina Aoki, Eri Kumagawa, Kazuaki Kamata, Hideo Ago, Naoki Sakai, Tomohisa Hasunuma, Naoaki Taoka, Yukari Ohta, Shingo Kobayashi   +8 more
doaj   +1 more source

State of the Art of Cyclic Lipopeptide–Membrane Interactions: Pore Formation and Bilayer Permeability

Pharmaceutics
Background/Objectives: Resistance of pathogenic microorganisms to antibiotics poses a serious threat to public health and often leads to devastating consequences. In this context, one of the pressing challenges in pharmacochemistry is the search for new,
Anastasiia A. Zakharova, Svetlana S. Efimova, Olga S. Ostroumova   +2 more
doaj   +1 more source

Genomic insights into a plant growth‐promoting Pseudomonas koreensis strain with cyclic lipopeptide‐mediated antifungal activity

MicrobiologyOpen, 2020
Strain S150 was isolated from the tobacco rhizosphere as a plant growth‐promoting rhizobacterium. It increased plant fresh weight significantly and lateral root development, and it antagonized plant pathogenic fungi but not phytobacteria.
Yilin Gu, Yi‐Nan Ma, Jing Wang, Zhenyuan Xia, Hai‐Lei Wei   +4 more
doaj   +1 more source

Identification, Isolation, and Characterization of Medipeptins, Antimicrobial Peptides From Pseudomonas mediterranea EDOX

Frontiers in Microbiology, 2021
The plant microbiome is a vastly underutilized resource for identifying new genes and bioactive compounds. Here, we used Pseudomonas sp. EDOX, isolated from the leaf endosphere of a tomato plant grown on a small farm in the Netherlands.
Lu Zhou, Anne de Jong, Yunhai Yi, Oscar P. Kuipers   +3 more
doaj   +1 more source

Evaluation of effect the cyclic lipopeptides from Bacillus atrophaeus HNSQJYH170 on Candida species

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2018
Background and Objectives: In humans, during the recent years, several factors have increased the risk of fungal infections, like broad spectrum antibiotics, immune compromised patients, cytotoxic chemotherapy and transplantations.
Solmaz Moghtadi pisheh, Mahboobeh madani
doaj