Results 51 to 60 of about 372,306 (310)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Strength degradation of sandstone and granodiorite under uniaxial cyclic loading

Journal of Rock Mechanics and Geotechnical Engineering, 2018
Change in mechanical properties of rocks under static loading has been widely studied and documented. However, the response of rocks to cyclic loads is still a much-debated topic.
Rashid Geranmayeh Vaneghi, Behnam Ferdosi, Achola D. Okoth, Barnabas Kuek   +3 more
doaj   +1 more source

Advanced fiber-composite hybrids--A new structural material [PDF]

, 1974
Introduction of metal foil as part of matrix and fiber composite, or ""sandwich'', improves strength and stiffness for multidirectional loading, improves resistance to cyclic loading, and improves impact and erosion resistance of resultant fiber ...
Chamis, C. C., Lark, R. F., Sullivan, T. L.   +2 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Comparative study on the fatigue behaviour of SCC and VC [PDF]

, 2014
Continuous cyclic loading on concrete constructions involves a progressive cracking mechanism, leading to significant changes of the material properties during the lifetime of the structure.
Boel, Veerle, De Corte, Wouter, De Schutter, Geert, Korte, Sara   +3 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Bearing Performance of a Helical Pile for Offshore Photovoltaic under Horizontal Cyclic Loading

Journal of Marine Science and Engineering
For an offshore photovoltaic helical pile foundation, significant horizontal cyclic loading is imposed by wind and waves. To study a fixed offshore PV helical pile’s horizontal cyclic bearing performance, a numerical model of the helical pile under ...
Xinfu Cong, Zhe Li, Zhonghai An, Jiangxue Liu, Yanqing Han   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Experimental study on deformation behaviors of saturated soft clay under intermittent cyclic loading with various drained conditions

Yantu gongcheng xuebao
In the previous studies, the cyclic triaxial tests under intermittent cyclic loading are used to study the deformation characteristics of soft clay under traffic loads. Both confining pressure and deviator stress vary cyclically in the stress field under
HUANG Juehao 1, 2, XU Linfeng 3, 1, LU Yuan 5, YAN Wenlong 4, 1, CHEN Jian 1, 2, FU Xiaodong 1, 2
doaj   +1 more source