Results 221 to 230 of about 157,149 (239)
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Synthesis of cyclic tryptathionine peptides
International Journal of Peptide and Protein Research, 1987The helicity of the tryptathionine moiety of the phallotoxins has been recognized by comparison with cyclic tryptathionine tripeptides. In order to investigate the influence of the configuration of the component amino acids on the conformation of the cyclic peptides, six analogue thioether tripeptides containing L‐ and D‐alanine and L‐ and D‐cysteine ...
Zanotti, G., Beijer, B., Wieland, T.
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Biopolymers, 1985
AbstractA multistep computational scheme was used to deduce possible conformations for a cyclic antagonist analog of somatostatin that has been reported by Coy and coworkers. An algebraic algorithm was used to find dihedral angles that give cyclic structures, the energy was computed for these structures, the lower‐energy structures were classified into
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AbstractA multistep computational scheme was used to deduce possible conformations for a cyclic antagonist analog of somatostatin that has been reported by Coy and coworkers. An algebraic algorithm was used to find dihedral angles that give cyclic structures, the energy was computed for these structures, the lower‐energy structures were classified into
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Cyclic Peptide Synthesis with Thioacids
Organic Letters, 2010C-Terminal amino acid 9-fluorenylmethylthioesters may be carried through Boc chemistry solution phase peptide synthesis sequences. After insertion of the final residue in the form of an Fmoc carbamate, treatment with piperidine releases a seco-peptide as a C-terminal thioacid that on treatment with Sanger's reagent undergoes cyclization to a cyclic ...
Sasaki, Kaname, Crich, David
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New cyclic peptide proteasome inhibitors
Bioorganic & Medicinal Chemistry Letters, 2009Here we report the study of a new series of vinyl ester cyclopeptide analogues synthesized on the basis of our previous development of a class of cyclopeptides derived from our linear prototype inhibitors. In these compounds, the exocyclic pharmacophoric unit Leu-VE was linked to the gamma-carboxyl group of the glutamic acid residue at the C-terminal ...
BALDISSEROTTO, Anna +3 more
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Synthesis of Cyclic Peptides and Cyclic Proteins via Ligation of Peptide Hydrazides
ChemBioChem, 2012Intramolecular ligation of peptide hydrazides is reported to occur readily, causing the lactamization of fully unprotected peptides in an epimerization-free manner. This method relies on the routine procedures of Fmoc solid-phase peptide synthesis. It can be used to prepare cyclic peptides and cyclic proteins under simpler, mild conditions at lower ...
Ji-Shen, Zheng +4 more
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Cyclic, Modified and Conjugated Peptides
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
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Cyclic peptides. Amino acid-cyclic peptides complexes
Journal of the American Chemical Society, 1974Charles M. Deber, Elkan R. Blout
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Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1983
A. Ravi, P. Balaram
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A. Ravi, P. Balaram
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