Results 261 to 270 of about 1,721,329 (334)

An mRNA-display derived cyclic peptide scaffold reveals the substrate binding interactions of an N-terminal cysteine oxidase. [PDF]

Nat Commun
Jiramongkol Y, Patel K, Johansen-Leete J, Maxwell JWC, Chang Y, Du JJ, Passioura T, Cook KM, Payne RJ, White MD.   +9 more
europepmc   +1 more source

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Flexibility-tuning of dual-display DNA-encoded chemical libraries facilitates cyclic peptide ligand discovery. [PDF]

Nat Commun
Petrov D, Plais L, Schira K, Cai J, Keller M, Lessing A, Bassi G, Cazzamalli S, Neri D, Gloger A, Scheuermann J.   +10 more
europepmc   +1 more source

Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion

Advanced Healthcare Materials, EarlyView.
We have developed a smart hair‐repair ingredient based on β‐carboxylic acid amide that undergoes negative‐to‐positive charge conversion under mildly acidic conditions. The initial negative charge facilitates deep penetration into the hair fiber, while the subsequent positive charge enables re‐bonding with sulfonate groups in damaged hair keratin.
Sunyoung Kang, Serena Serin Park, Sugyeong Jeong, Seoyeon Kyung, Minjae Kim, Seok Kyun Yun, Hyun‐Na Kim, Seunghyun Kang, Yan Lee   +8 more
wiley   +1 more source

Unveiling cyclic tetra amino acids-based peptides as insulin degrading enzyme inhibitors: insight from <i>Insilico</i> approach

Faith Eniola Olujinmi, Abel Kolawole Oyebamiji, Halleluyah Oluwatobi Aworinde, David Gbenga Oke, Sunday Aewale Akintelu, Emmanuel T. Akintayo, Cecilia O. Akintayo, Jonathan O. Babalola   +7 more
openalex   +2 more sources

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

Advanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz, Noa Ben David, Adi Gross, Boaz Mizrahi   +3 more
wiley   +1 more source

Cyclic Peptide Natural Product Inspired Inhibitors of the Free-Living Amoeba <i>Balamuthia mandrillaris</i>. [PDF]

J Nat Prod
Lu C, Nelson S, Coy G, Neumann C, Parkinson EI, Rice CA.   +5 more
europepmc   +1 more source

Transparent Multifunctional Wearable Strain Sensor With Self‐Healing and Antibacterial Capabilities for Human Motion Detection

Advanced Healthcare Materials, EarlyView.
A transparent dual‐network strain sensor integrates robust mechanical properties, room‐temperature self‐healing, and stable performance under sub‐zero conditions and prolonged storage. Its excellent biocompatibility and antimicrobial properties enable safe skin contact.
Wenqing Chen, Wei Huang, Rohit Gupta, Abbas Heydari, Biswajoy Bagchi, Lulu Xu, Yang Xue, Eirini Velliou, Manish K Tiwari   +8 more
wiley   +1 more source

Author Correction: Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α. [PDF]

Sci Rep
Ismail M, Martin SR, George R, Houghton F, Kelly G, Chaleil RAG, Anastasiou P, Wang X, O'Reilly N, Federico S, Joshi D, Nagaraj H, Cooley R, Hui NS, Molina-Arcas M, Hancock DC, Tavassoli A, Downward J.   +17 more
europepmc   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source