Results 291 to 300 of about 211,010 (331)
ImmunoPET imaging of LAG-3 expression in tumor microenvironment with 68Ga-labelled cyclic peptides tracers: from bench to bedside. [PDF]
J Immunother CancerZhou M +6 more
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Cyclic peptides targeting the SARS-CoV-2 programmed ribosomal frameshifting RNA from a multiplexed phage display library. [PDF]
Chem SciIannuzzelli JA +6 more
europepmc +1 more source
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International Journal of Peptide and Protein Research, 1986
In order to investigate the role of the L‐2‐hydroxy‐3‐methylbutanoic acid residue at position 2 of AM‐toxin I (cyclic tetradepsipeptide) on necrotic activity for apple leaves, two analogs, [L‐lactic acid2] AM‐toxin I and [L‐2‐hydroxy‐4‐methylpentanoic acid2] AM‐toxin I, were synthesized by the conventional method for peptide synthesis.
HISAKAZU MIHARA +6 more
+4 more sources
In order to investigate the role of the L‐2‐hydroxy‐3‐methylbutanoic acid residue at position 2 of AM‐toxin I (cyclic tetradepsipeptide) on necrotic activity for apple leaves, two analogs, [L‐lactic acid2] AM‐toxin I and [L‐2‐hydroxy‐4‐methylpentanoic acid2] AM‐toxin I, were synthesized by the conventional method for peptide synthesis.
HISAKAZU MIHARA +6 more
+4 more sources
International Journal of Peptide and Protein Research, 1985
cyclo(‐l‐Pro‐l‐Val‐l‐Pro‐l‐Val‐) (1L) and cyclo(‐l‐Pro‐d‐Val‐l‐Pro‐d‐Val‐) (1D) were synthesized by the conventional method for peptide synthesis. Conformations of 1L and 1D in solution were studied. Compound 1L has a cis‐trans‐cis‐trans backbone conformation with C2 symmetry in CDCl3.
TOSHIHISA UEDA +3 more
openaire +1 more source
cyclo(‐l‐Pro‐l‐Val‐l‐Pro‐l‐Val‐) (1L) and cyclo(‐l‐Pro‐d‐Val‐l‐Pro‐d‐Val‐) (1D) were synthesized by the conventional method for peptide synthesis. Conformations of 1L and 1D in solution were studied. Compound 1L has a cis‐trans‐cis‐trans backbone conformation with C2 symmetry in CDCl3.
TOSHIHISA UEDA +3 more
openaire +1 more source
International Journal of Peptide and Protein Research, 1980
Å number of cyclo (Δaminoacyl‐L‐aminoacyl) (Δaminoacyl =ΔAba, ΔVal, ΔLeu, ΔApp, ΔPhe and ΔTrp; L‐aminoacyl=L‐Ala, L‐Val, L‐Leu and L‐Lys (e‐Ac)) were synthesized by the condensation of cyclo (N‐acetyl‐Gly‐N‐acetyl‐L‐aminoacyl) with corresponding aldehyde or acetone and subsequent treatment with hydrazine. Each cyclo (Δaminoacyl‐L‐aminoacyl) except ones
TATSUHIKO KANMERA +3 more
openaire +1 more source
Å number of cyclo (Δaminoacyl‐L‐aminoacyl) (Δaminoacyl =ΔAba, ΔVal, ΔLeu, ΔApp, ΔPhe and ΔTrp; L‐aminoacyl=L‐Ala, L‐Val, L‐Leu and L‐Lys (e‐Ac)) were synthesized by the condensation of cyclo (N‐acetyl‐Gly‐N‐acetyl‐L‐aminoacyl) with corresponding aldehyde or acetone and subsequent treatment with hydrazine. Each cyclo (Δaminoacyl‐L‐aminoacyl) except ones
TATSUHIKO KANMERA +3 more
openaire +1 more source
International Journal of Peptide and Protein Research, 1984
In order to explore the route for cyclization of linear oligopeptide containing a ΔAla (α, β‐dehydroalanine) residue, AM‐toxin II was synthesized. As a preliminary experiment, synthesis of [L‐Phe3] AM‐toxin II, containing L‐Phe in place of L‐App (L‐2‐amino‐5‐phenylpentanoic acid), was attempted.
TOSHIRO KOZONO +4 more
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In order to explore the route for cyclization of linear oligopeptide containing a ΔAla (α, β‐dehydroalanine) residue, AM‐toxin II was synthesized. As a preliminary experiment, synthesis of [L‐Phe3] AM‐toxin II, containing L‐Phe in place of L‐App (L‐2‐amino‐5‐phenylpentanoic acid), was attempted.
TOSHIRO KOZONO +4 more
openaire +1 more source
International Journal of Peptide and Protein Research, 1981
In order to establish possible routes for the synthesis of AM‐toxins, cyclotetradepsipeptides containing Dha, Pyr‐L‐Ala‐L‐Hmb‐L‐Tyr‐NH2 were prepared and treated with TFA or anhydrous HF. The product was identified to be cyclo (‐α‐Hyala‐L‐Ala‐L‐Hmb‐L‐Tyr‐), resulting from intramolecular condensation of the α‐keto and amide group with the formation of ...
Kosaku Noda +4 more
openaire +1 more source
In order to establish possible routes for the synthesis of AM‐toxins, cyclotetradepsipeptides containing Dha, Pyr‐L‐Ala‐L‐Hmb‐L‐Tyr‐NH2 were prepared and treated with TFA or anhydrous HF. The product was identified to be cyclo (‐α‐Hyala‐L‐Ala‐L‐Hmb‐L‐Tyr‐), resulting from intramolecular condensation of the α‐keto and amide group with the formation of ...
Kosaku Noda +4 more
openaire +1 more source