Results 21 to 30 of about 207,671 (274)
Impact of Peptide Structure on Colonic Stability and Tissue Permeability
Pharmaceutics, 2023 Most marketed peptide drugs are administered parenterally due to their inherent gastrointestinal (GI) instability and poor permeability across the GI epithelium.
Farhan Taherali +7 more
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Beilstein Journal of Organic Chemistry, 2008 We present a mechanistic investigation of Pd-catalyzed allylic substitution of cyclic gem-difluorinated carbonates 1 and 4, previously employed in the synthesis of 3',3'-difluoro-2'-hydroxymethyl-4',5'-unsaturated carbocyclic nucleosides in 17 steps. The
Jun Xu, Xiao-Long Qiu, Feng-Ling Qing
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N-Borane-Substituted Cyclic Phosphine Imides (BCPIs)
Bulletin of the Chemical Society of Japan, 2023 Phosphine imides are ubiquitous nucleophiles/Lewis bases in modern organic chemistry. The introduction of unexplored substituents on the phosphine imidoyl nitrogen and/or phosphorus atoms should facilitate the discovery of unprecedented utility for phosphine imides.
Shun Nagai +3 more
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Predicting B cell receptor substitution profiles using public repertoire data. [PDF]
PLoS Computational Biology, 2018 B cells develop high affinity receptors during the course of affinity maturation, a cyclic process of mutation and selection. At the end of affinity maturation, a number of cells sharing the same ancestor (i.e.
Amrit Dhar +3 more
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Approach to the Synthesis of Five-Membered Organophosphorus Compounds via Alumoles and Alumolanes
Chemistry Proceedings, 2022 This work summarizes the results of a new approach to the synthesis of previously undescribed, hard-to-obtain five-membered cyclic organophosphorus compounds: 3-alkyl(aryl)-substituted phospholanes, α,ω-bisphospholanes, polycyclic phospholanes, 4,5 ...
Alevtina L. Makhamatkhanova +2 more
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Beilstein Journal of Organic Chemistry, 2013 In this work, we introduce a new class of halodiazocarbonyl compounds, α-halodiazoacetamides, which through a metal-free, ambient-temperature thermolysis perform intramolecular C–H insertions to produce α-halo-β-lactams.
Åsmund Kaupang, Tore Bonge-Hansen
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Synthesis and Characterization of New Cyclic Aminobenzoquinones
Journal of the Turkish Chemical Society, Section A: Chemistry, 2018 The aim of this research is to synthesize and characterize of new cyclic members of cyclic aminobenzoquinones. Mono amino substituted products; 2-chloro-5,6-dimethyl-3-(pyrrolidin-1-yl)-1,4-benzoquinone (2), 2-chloro-5,6-dimethyl-3-(piperidin-1-yl)-1,4 ...
Amaç Fatih Tuyun, Mahmut Yıldız
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Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87) [PDF]
, 2001 Urokinase-type plasminogen activator (uPA) represents a central molecule in pericellular proteolysis and is implicated in a variety of physiological and pathophysiological processes such as tissue remodelling, wound healing, tumor invasion, and ...
Arroyo de Prada, Nuria +10 more
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MODIFICATION OF THE ENERGY-SATURATED HETEROGENEOUS COMPOSITE MATERIAL BY CYCLIC NITRAMINES
Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2018 Several methods have been described for increasing the main characteristics (density, heat of combustion, combustion temperature, gas formation index) and operating properties (combustion speed and temperature, total and specific impulse, properties of ...
A. Ph. Ilyushchanka +2 more
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AdS/CFT as classical to quantum correspondence in a Virtual Extra Dimension [PDF]
, 2013 The correspondence between classical extra dimensional geometry and quantum behavior, typical of the AdS/CFT, has a heuristic semiclassical interpretation in terms of undulatory mechanics and relativistic geometrodynamics.
Dolce, Donatello
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