Results 171 to 180 of about 518,198 (339)

Author response: Orderly assembly underpinning built-in asymmetry in the yeast centrosome duplication cycle requires cyclin-dependent kinase

, 2020
Marco Geymonat, Qiuran Peng, Zhiang Guo, Zulin Yu, Jay R. Unruh, Sue L. Jaspersen, Marisa Segal   +6 more
openalex   +1 more source

Costunolide Induces Apoptosis via Modulation of Cyclin-Dependent Kinase in HL-60 Human Leukemia Cells [PDF]

, 2010
Dong Hee Kim, Jung‐Hye Choi, Hee-Juhn Park, Jae‐Hoon Park, Kyung‐Tae Lee   +4 more
openalex   +1 more source

Cyclin-dependent kinase 1–dependent activation of APC/C ubiquitin ligase

Science, 2016
K. Fujimitsu, M. Grimaldi, H. Yamano
semanticscholar   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Spatiotemporal orchestration of mitosis by cyclin-dependent kinase. [PDF]

Nature
Kapadia N, Nurse P.
europepmc   +2 more sources

Cyclins That Don’t Cycle : Cyclin T/Cyclin-Dependent Kinase-9 Determines Cardiac Muscle Cell Size [PDF]

, 2003
Motoaki Sano, Michael Schneider
openalex   +1 more source

Dynamics of natural killer cell function upon recurrent stimulation

Biotechnology Progress, EarlyView.
Weekly stimulation of peripheral blood‐derived NK cells with engineered K562 feeder cells resulted in two distinct growth phases, shifting around Day 21–26. Cells in growth phase 2 exhibited slower growth, reduced metabolic activity, and lower cytotoxicity than cells from growth phase 1, which has implications for NK cell biomanufacturing.
Jennifer One, Janani Narayan, Frank Cichocki, Wei‐Shou Hu, Samira M. Azarin   +4 more
wiley   +1 more source

Longitudinal Tumor Size and Survival Modeling for Exposure–Response Analysis of Drugs with Frequent Dose Reductions: Dose Justification of Abemaciclib in Patients with Metastatic Breast Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Abemaciclib is an oral anticancer drug indicated for treatment of HR+ HER2‐ breast cancer. Dose modifications due to side effects are frequent, thus drug exposures change over time as a result of altering the dose or temporarily withholding abemaciclib treatment.
Emmanuel Chigutsa, Sonya C. Chapman, P. Kellie Turner   +2 more
wiley   +1 more source

Cyclin-Dependent Kinase 4–Mediated Phosphorylation Inhibits Smad3 Activity in Cyclin D–Overexpressing Breast Cancer Cells [PDF]

, 2010
Stanislav Zelivianski, Anne Cooley, Ron Kall, Jacqueline S. Jeruss   +3 more
openalex   +1 more source

Molecular and cellular effects of the combined treatment with Camptothecin and Roscovitine in human lung and colon adenocarcinoma cells [PDF]

, 2008
De Mattia, Roberta
core   +1 more source