Results 211 to 220 of about 504,196 (405)

Cyclin-dependent kinase inhibitor therapy for hematologic malignancies

open access: yesExpert Opinion on Investigational Drugs, 2013
P. Bose, G. Simmons, S. Grant
semanticscholar   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Continuing Cyclin-Dependent Kinase 4/6 Inhibitors Beyond Progression in Advanced Breast Cancer: A Meta-Analysis. [PDF]

open access: yesCancers (Basel)
Pathak N   +13 more
europepmc   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

Cyclin-dependent kinase 13 is indispensable for normal mouse heart development. [PDF]

open access: yesJ Anat
Waheed-Ullah Q   +8 more
europepmc   +1 more source

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