Safety and Efficacy of a Selective Inhibitor of Cyclin-dependent Kinase 9 (KB-0742) in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma. [PDF]
Hanna GJ+9 more
europepmc +1 more source
A Protein Encoded by the Latency-Related Gene of Bovine Herpesvirus 1 Is Expressed in Trigeminal Ganglionic Neurons of Latently Infected Cattle and Interacts with Cyclin-Dependent Kinase 2 during Productive Infection [PDF]
Yunquan Jiang+5 more
openalex +1 more source
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu+8 more
wiley +1 more source
TGF-β1 Induces the Cyclin-Dependent Kinase Inhibitor p27Kip1 mRNA and Protein in Murine B Cells [PDF]
H Kamesaki+4 more
openalex +1 more source
Molecular subtyping and precision therapy for esophageal cancer
The molecular typing of esophageal cancer based on genome, transcriptome, proteome, and multi‐omics revealed various molecular features and provided potential targets for the precision therapy. Recent trials have shown that immunotherapy or molecular targeted therapy plus chemoradiotherapy can improve overall survival and progression‐free survival in ...
Guangkun Pei+5 more
wiley +1 more source
A meta-analysis and systematic review of different cyclin-dependent kinase 4/6 inhibitors in breast cancer. [PDF]
Zhang J, Xu X, Zhou Y, Su J, Wang J.
europepmc +1 more source
The Cyclin-dependent Kinase Inhibitor p21 Mediates the Growth Inhibitory Effect of Phorbol Esters in Human Venous Endothelial Cells [PDF]
Jürgen Zezula+5 more
openalex +1 more source
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang+12 more
wiley +1 more source