Role of the cyclin-dependent kinase inhibitors in the development of cancer [PDF]
Toshiyasu Hirama, HP Koeffler
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Cyclin-dependent kinase inhibitor therapy for hematologic malignancies
P. Bose, G. Simmons, S. Grant
semanticscholar +1 more source
Drug design for cyclin-dependent kinase 9 (CDK9) inhibitors <i>in silico</i>. [PDF]
Asamitsu K, Hirokawa T, Okamoto T.
europepmc +1 more source
S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state [PDF]
Christian Dahmann+2 more
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Cyclin-Dependent Kinase Inhibition in Prostate Cancer: Past, Present, and Future. [PDF]
Siskin M, Economides MP, Wise DR.
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Continuing Cyclin-Dependent Kinase 4/6 Inhibitors Beyond Progression in Advanced Breast Cancer: A Meta-Analysis. [PDF]
Pathak N+13 more
europepmc +1 more source
Role of PPARγ in Regulating a Cascade Expression of Cyclin-dependent Kinase Inhibitors, p18(INK4c) and p21(Waf1/Cip1), during Adipogenesis [PDF]
Ron F. Morrison, Stephen R. Farmer
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Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner+3 more
wiley +1 more source
Cyclin-dependent kinase 13 is indispensable for normal mouse heart development. [PDF]
Waheed-Ullah Q+8 more
europepmc +1 more source