Identification of novel cyclin-dependent kinase 4/6 inhibitors from marine natural products. [PDF]
Debnath A+3 more
europepmc +1 more source
Four‐gene Prognostic Signature and Risk of Brain Metastasis of Lung Adenocarcinoma
ABSTRACT Brain metastasis has a high incidence and poor prognosis in lung adenocarcinoma (LUAD). We sought to identify genes associated with LUAD brain metastasis and with the prognosis of patients with LUAD. Differential gene expression analysis was performed on LUAD patients with and without distant metastasis from the Cancer Genome Atlas (TCGA ...
Zheng Gong+11 more
wiley +1 more source
Cyclin-dependent kinase 5 (CDK5) inhibitors in Parkinson disease. [PDF]
Alrouji M+7 more
europepmc +1 more source
Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6 [PDF]
Ursula Schulze‐Gahmen+2 more
openalex +1 more source
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock. [PDF]
Brenna A+7 more
europepmc +1 more source
Cyclin-dependent Kinase Inhibitor p16INK4A Inhibits Phosphorylation of RNA Polymerase II by General Transcription Factor TFIIH [PDF]
Hiroaki Serizawa
openalex +1 more source
Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti+4 more
wiley +1 more source
The Cyclin-Dependent Kinase 8 Inhibitor E966-0530-45418 Attenuates Pulmonary Fibrosis In Vitro and In Vivo. [PDF]
Chou CH+5 more
europepmc +1 more source