Results 251 to 260 of about 504,196 (405)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

18F-FLT PET, a Noninvasive Pharmacodynamic Biomarker of Tumor Cell Proliferation, Detected Differential Response to Various Cyclin-Dependent Kinase (CDK) Inhibitors. [PDF]

Mol Cancer Ther
Giddabasappa A, Jiang ZK, Yang B, Chen L, Liu F, Cabral E, Ram S, Boras B, Huser N, Zhang CC, Noorbehesht K, Manzuk LK, Visswanathan R, Mojtahedzadeh S, Affolter T, Carmody J, Kang AN, Petroski MD, Khamphavong PL, VanArsdale T, Nguyen QD, Maresca KP, Dann SG.   +22 more
europepmc   +1 more source

Identification of Substrate Binding Site of Cyclin-dependent Kinase 5 [PDF]

, 1999
Pushkar Sharma, Peter Steinbach, Monica Sharma, Niranjana D. Amin, Joseph J. Barchi, Harish C. Pant   +5 more
openalex   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Caregivers' Perceptions of Clinical Symptoms, Disease Management, and Quality of Life Impact in Cases of Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Cross-Sectional Online Survey. [PDF]

JMIR Form Res
Amin S, Partridge CA, Leonard H, Downs J, Allvin H, Ficara V, Pain E, Korolainen MA.   +7 more
europepmc   +1 more source

Epidermal growth factor increases the level of the cyclin-dependent kinase (CDK) inhibitor p21/CIP1 (CDK-interacting protein 1) in A431 cells by increasing the half-lives of the p21/CIP1 transcript and the p21/CIP1 protein [PDF]

, 1999
Lene E. Johannessen, Sigrun L. Knardal, Inger Helene Madshus   +2 more
openalex   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

Safety and Efficacy of a Selective Inhibitor of Cyclin-dependent Kinase 9 (KB-0742) in Patients with Recurrent or Metastatic Adenoid Cystic Carcinoma. [PDF]

Cancer Res Commun
Hanna GJ, Cote GM, Chugh R, Thomas JS, Malhotra J, Cutler RE, Hood T, Carvajal LA, Olek EA, Villalona-Calero MA.   +9 more
europepmc   +1 more source

Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment

Molecular Nutrition &Food Research, EarlyView.
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti, Martina Giuseffi, Eugenia Giglio, Graziella Marino, Marisabel Mecca   +4 more
wiley   +1 more source

A meta-analysis and systematic review of different cyclin-dependent kinase 4/6 inhibitors in breast cancer. [PDF]

Front Oncol
Zhang J, Xu X, Zhou Y, Su J, Wang J.
europepmc   +1 more source