Results 261 to 270 of about 504,196 (405)

Grape Seed Proanthocyanidins: A Potential Microbiome‐Targeted Intervention for Healthy Aging in Rats

open access: yesMolecular Nutrition &Food Research, EarlyView.
Grape seed proanthocyanidin extract (GSPE) promotes a healthier gut phenotype in aged rats. Aging alters gut microbiota composition, increases inflammation, and compromises intestinal barrier function. This study shows that short‐term GSPE treatment in aged rats partially restores microbial diversity toward a youthful profile, modulates mucus‐related ...
Marta Sierra‐Cruz   +10 more
wiley   +1 more source

Gallstone Ileus in a 25-Year-Old Female With Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: A Case Report. [PDF]

open access: yesCase Rep Gastrointest Med
Onoda H   +7 more
europepmc   +1 more source

Concentration‐Based Analysis of Metal‐Induced Tau Fibrillar versus non‐fibrillar Aggregation: Implications for Neurotoxicity in Alzheimer's Disease

open access: yesChemistryOpen, EarlyView.
Tau protein aggregation and fibrillation have been examined in relationship to three metal ions in this study. The research was conducted to see the effects of Zn2+, Cu2+ and Fe3+ ions at different concentrations on tau′s conformation, cytotoxicity in SH‐SY5Y cells, and free thiol levels.
Mahzad Irandoust   +6 more
wiley   +1 more source

Salen‐Type Copper(II) Complexes: Synthesis, Characterization, Computational Studies, Molecular Docking, Anticancer Potential, and Pharmacokinetic Prediction

open access: yesChemistryOpen, EarlyView.
Integrating synthesis, density functional theory studies, molecular docking, cytotoxicity, and ADMET predictions, this study identifies [CuII(salen)(H2O)2] (2) as a selective anticancer agent. Docking and in vitro assays highlight its favorable target interactions, selective anticancer activity, and reduced toxicity toward normal fibroblasts ...
Abdellatif A. Helaly   +8 more
wiley   +1 more source

Raddeanin A exerts potent efficacy against non-small cell lung cancer by inhibiting cyclin-dependent kinase 6. [PDF]

open access: yesTransl Oncol
Wang X   +10 more
europepmc   +1 more source

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