Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6 [PDF]
Ursula Schulze‐Gahmen+2 more
openalex +1 more source
Molecular and cellular effects of the combined treatment with Camptothecin and Roscovitine in human lung and colon adenocarcinoma cells [PDF]
De Mattia, Roberta
core +1 more source
Grape Seed Proanthocyanidins: A Potential Microbiome‐Targeted Intervention for Healthy Aging in Rats
Grape seed proanthocyanidin extract (GSPE) promotes a healthier gut phenotype in aged rats. Aging alters gut microbiota composition, increases inflammation, and compromises intestinal barrier function. This study shows that short‐term GSPE treatment in aged rats partially restores microbial diversity toward a youthful profile, modulates mucus‐related ...
Marta Sierra‐Cruz+10 more
wiley +1 more source
Gallstone Ileus in a 25-Year-Old Female With Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: A Case Report. [PDF]
Onoda H+7 more
europepmc +1 more source
G1–checkpoint Function Including a Cyclin‐dependent Kinase 2 Regulatory Pathway as Potential Determinant of 7–Hydroxystaurosporine (UCN‐01)‐induced Apoptosis and G1–phase Accumulation [PDF]
Tadakazu Akiyama+4 more
openalex +1 more source
Tau protein aggregation and fibrillation have been examined in relationship to three metal ions in this study. The research was conducted to see the effects of Zn2+, Cu2+ and Fe3+ ions at different concentrations on tau′s conformation, cytotoxicity in SH‐SY5Y cells, and free thiol levels.
Mahzad Irandoust+6 more
wiley +1 more source
Cyclin-Dependent Kinase 4/6 Inhibitors Combined with Radiotherapy in Curative Breast Cancer Patients Induced Pneumonitis: A Case Report. [PDF]
Hou PY.
europepmc +1 more source
Integrating synthesis, density functional theory studies, molecular docking, cytotoxicity, and ADMET predictions, this study identifies [CuII(salen)(H2O)2] (2) as a selective anticancer agent. Docking and in vitro assays highlight its favorable target interactions, selective anticancer activity, and reduced toxicity toward normal fibroblasts ...
Abdellatif A. Helaly+8 more
wiley +1 more source
Raddeanin A exerts potent efficacy against non-small cell lung cancer by inhibiting cyclin-dependent kinase 6. [PDF]
Wang X+10 more
europepmc +1 more source