Results 271 to 280 of about 384,579 (349)

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A [PDF]

, 2017
Steven P. O’Hara, Patrick L. Splinter, Christy E. Trussoni, María J. Lorenzo Pisarello, Lorena Loarca, Noah S. Splinter, Bryce F. Schutte, Nicholas F. LaRusso   +7 more
openalex   +1 more source

Functional and Spatial Regulation of Mitotic Centromere- Associated Kinesin by Cyclin-Dependent Kinase 1

Molecular and Cellular Biology, 2010
M. Sanhaji, Claire T. Friel, N. Kreis, A. Krämer, Claudia Martin, J. Howard, K. Strebhardt, Juping Yuan   +7 more
semanticscholar   +1 more source

Treatment of pediatric epilepsy

Pediatric Investigation, EarlyView.
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li, Tinghong Liu, Chang Liu, Jie Deng, Shijie Wu, Suhui Kuang, Xiaotong Li, Zhirong Wei, Shuli Liang   +8 more
wiley   +1 more source

Cyclin-dependent kinase 1-mediated phosphorylation of SET at serine 7 is essential for its oncogenic activity. [PDF]

Cell Death Dis, 2019
Yin L, Zeng Y, Xiao Y, Chen Y, Shen H, Dong J.   +5 more
europepmc   +1 more source

Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program

, 2012
Richard Görlick, E. Anders Kolb, Peter J. Houghton, Christopher L. Morton, Geoffrey Neale, Stephen T. Keir, Hernán Carol, Richard B. Lock, Doris A. Phelps, Min H. Kang, C. Patrick Reynolds, John M. Maris, Catherine A. Billups, Malcolm A. Smith   +13 more
openalex   +2 more sources

Inhibitory Phosphorylation of Cyclin-Dependent Kinase 1 as a Compensatory Mechanism for Mitosis Exit

Molecular and Cellular Biology, 2011
J. Chow, R. Poon, H. Ma
semanticscholar   +1 more source

Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection

PROTEOMICS, EarlyView.
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren, Kenneth Weke, Darryl Hardie, Mariya I. Goncheva, Ted Hupp, Javier Antonio Alfaro, Helena Pětrošová, David R. Goodlett   +7 more
wiley   +1 more source

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and "cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats. [PDF]

Cell Transplant, 2020
Gao L, Wang C, Qin B, Li T, Xu W, Lenahan C, Ying G, Li J, Zhao T, Zhu Y, Chen G.   +10 more
europepmc   +1 more source

Phase 1 Study Evaluating the Association of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib and Cetuximab in Recurrent/Metastatic p16-Negative Squamous Cell Carcinoma of the Head and Neck [PDF]

, 2019
Emmanuel Seront, Sandra Schmitz, M. Papier, Aline van Maanen, Stéphanie Henry, Christophe Lonchay, Sylvie Rottey, Gabrielle van Caloen, Jean‐Pascal Machiels   +8 more
openalex   +1 more source