Role of the CDKN1A/p21, CDKN1C/p57, and CDKN2A/p16 Genes in the Risk of Atherosclerosis and Myocardial Infarction [PDF]
Atherosclerosis is characterized by excessive proliferation of neointimal leukocytes and vascular smooth muscle cells (VSMCs). In mice, the manipulation of cell cycle inhibitors such as CDKN1B (p27) and CDKN1A (p21) modifies the risk of developing ...
Andrés, Vicente +8 more
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Detection of homozygous deletions of the cyclin-dependent kinase 4 inhibitor (p16) gene in acute lymphoblastic leukemia and association with adverse prognostic features [PDF]
Marco Fizzotti +7 more
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The p16, p15 and p14 genes are widely known as tumor suppressor genes in human medicine. Although a large number of genetic and epigenetic aberrations in these genes have been reported in human malignancies, canine malignancies have not been well analyzed on the aberrations of these genes.
Aki, Fujiwara-Igarashi +6 more
openaire +1 more source
Differential Effects of the Cyclin-Dependent Kinase Inhibitors p27 Kip1 , p21 Cip1 , and p16 Ink4 on Vascular Smooth Muscle Cell Proliferation [PDF]
Felix C. Tanner +7 more
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Hemizygous deletion of cyclin-dependent kinase inhibitor 2A/B with p16 immuno-negative and methylthioadenosine phosphorylase retention predicts poor prognosis in IDH-mutant adult glioma [PDF]
Ryosuke Otsuji +13 more
openalex +1 more source
Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood [PDF]
Seisho Takeuchi +9 more
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Precision targeting of <i>CCNE1</i>-amplified tumors-lessons from BLU-222 and beyond. [PDF]
Rantanen F, Ungureanu D.
europepmc +1 more source
Loss of chromosome arm 9p DNA and analysis of the p16 and p15 cyclin-dependent kinase inhibitor genes in human parathyroid adenomas. [PDF]
Hideki Tahara +3 more
openalex +1 more source
Histological and Genetic Markers of Cellular Senescence in Keratinocyte Cancers and Actinic Keratosis: A Systematic Review. [PDF]
Sobolewski P +4 more
europepmc +1 more source

